{"id":"W4416643524","doi":"10.1055/s-0042-1754605","title":"Wirksamkeit und Sicherheit einer Guselkumab Induktionstherapie bei Patient:innen mit mittelschwerer bis schwerer aktiver Colitis ulcerosa: Ergebnisse der Phase-2b-Studie QUASAR über 12 Wochen","year":2022,"lang":"de","type":"article","venue":"Zeitschrift für Gastroenterologie","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Complication; Congenital disease; Sacrum; Ulcerative colitis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002792508,0.0006551669,0.002040098,0.0002559832,0.0003110956,0.001153431,0.0003529228,0.0009342453,0.003996304],"category_scores_gemma":[0.003410751,0.0003600063,0.002506806,0.000292125,0.0004703005,0.0009517237,0.0004733245,0.002169114,0.0006363916],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003927905,"about_ca_system_score_gemma":0.0008042296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004347281,"about_ca_topic_score_gemma":0.0007572576,"domain_scores_codex":[0.9991937,0.0003671709,0.00008112222,0.00009657639,0.0001132502,0.0001481949],"domain_scores_gemma":[0.9987035,0.000590928,0.0003169671,0.00007868437,0.0001031865,0.0002067874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6772137,0.02738028,0.02600122,0.005035408,0.008435669,0.000178347,0.0006211365,0.001344997,0.01786817,0.0002119832,0.002429277,0.2332798],"study_design_scores_gemma":[0.1596615,0.7398303,0.07101226,0.00100201,0.01095933,0.0005908098,0.0004814614,0.001051569,0.007476535,0.0004473536,0.007369588,0.0001174623],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876381,0.009879239,0.0002614008,0.0003436028,0.0001056376,0.0003729991,0.000537503,0.00001795359,0.0008435365],"genre_scores_gemma":[0.9898883,0.006222692,0.0007287692,0.0005728555,0.000138769,0.0006154575,0.0009029005,0.00001801888,0.0009122525],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003996304,"threshold_uncertainty_score":0.01476836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01517917140340915,"score_gpt":0.2769624430952127,"score_spread":0.2617832716918035,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}