{"id":"W4416649241","doi":"10.7554/elife.102068.3","title":"β-Glucan reprograms alveolar macrophages via neutrophil/IFNγ axis in a murine model of lung injury","year":2025,"lang":"en","type":"article","venue":"eLife","topic":"Immune responses and vaccinations","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research; Fonds de Recherche du Québec - Santé; Royal Society of Canada","keywords":"Reprogramming; Haematopoiesis; Immunity; Inflammation; Inducer; Immune system; Lung; Innate immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002655842,0.0001418689,0.0002931683,0.0002810858,0.00009590544,0.000007744591,0.0002247023,0.0001790119,0.0001419951],"category_scores_gemma":[0.00009499485,0.0001353862,0.0001161331,0.0003634969,0.00007806693,0.00006002277,0.0001524849,0.0002711035,0.00003796002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004646274,"about_ca_system_score_gemma":0.0001090503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003796886,"about_ca_topic_score_gemma":0.00004266726,"domain_scores_codex":[0.9988911,0.0001386055,0.0003982165,0.0002563749,0.00003167271,0.0002840814],"domain_scores_gemma":[0.9993158,0.00007035206,0.00009326122,0.0004186482,0.00008951632,0.00001244473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001064886,0.000655657,0.01627734,0.0001055512,0.0003033915,0.000008251586,0.0005760555,0.000422678,0.939169,0.004708102,0.005068729,0.03164029],"study_design_scores_gemma":[0.005469195,0.0004976656,0.1254948,0.0002730376,0.0001591067,0.00002873311,0.0003079824,0.005796285,0.830245,0.001031661,0.03008993,0.0006066578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898698,0.007158516,0.0008968919,0.0007065291,0.0002977397,0.0002802721,0.00003492613,0.00005503936,0.0007003138],"genre_scores_gemma":[0.9928903,0.0003670857,0.0002088974,0.0001903795,0.00000984191,0.00004266204,0.00004157207,0.00001230069,0.00623696],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1092174,"threshold_uncertainty_score":0.5520889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007708506014011538,"score_gpt":0.2744181869529735,"score_spread":0.266709680938962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}