{"id":"W4416670275","doi":"10.1101/2025.11.23.690023","title":"Transgenerational plasticity affects fitness and mediates local adaptation","year":2025,"lang":"","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Animal Behavior and Reproduction","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; National Science Foundation","keywords":"Grandparent; Transgenerational epigenetics; Offspring; Phenotypic plasticity; Allele; Adaptation (eye); Maternal effect","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001522752,0.0002293448,0.0001960351,0.0002897045,0.0001404047,0.000332655,0.0003079999,0.0001934788,0.001562449],"category_scores_gemma":[0.000282207,0.0001426671,0.0001235706,0.0001342601,0.0003053029,0.0002642452,0.0005613776,0.0004994984,0.0001740798],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002477853,"about_ca_system_score_gemma":0.0000972828,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005503697,"about_ca_topic_score_gemma":0.001105016,"domain_scores_codex":[0.9998802,0.00001764208,0.000007131261,0.0000538838,0.00002045641,0.00002062313],"domain_scores_gemma":[0.9997622,0.000041974,0.00006818168,0.00005740855,0.000018924,0.00005125673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00004282852,0.00002255564,0.005425459,0.00001628174,0.000009547801,0.00005152664,0.00003888089,0.0001459968,0.9915375,0.0001806915,0.00003345112,0.002495435],"study_design_scores_gemma":[0.00001731294,0.000370349,0.7172771,0.00002357914,0.00004705695,0.0005716304,0.0002352655,0.007837718,0.2704898,0.000898137,0.002198168,0.00003395752],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980932,0.00007953045,0.001015954,0.00002851404,0.000004086042,0.00000283233,0.00007146871,0.00005776849,0.000646734],"genre_scores_gemma":[0.9991104,0.00002346937,0.000348114,0.00001922828,0.000002290297,0.000004521513,0.00005716097,0.00001637641,0.0004184659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001562449,"threshold_uncertainty_score":0.00522691,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02081489270333858,"score_gpt":0.2146452578804214,"score_spread":0.1938303651770828,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}