{"id":"W4416685624","doi":"10.1016/j.jcjd.2025.10.146","title":"Long-Term Efficacy and Safety of Palopegteriparatide Treatment in Adults With Chronic Hypoparathyroidism: 4-Year Results From the Phase 2 PaTH Forward Trial","year":2025,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Thyroid and Parathyroid Surgery","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Phase (matter); Clinical trial; Hypoparathyroidism; Path (computing); Phases of clinical research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002591159,0.00125459,0.002877089,0.0002867537,0.000425641,0.001327959,0.000670179,0.001918856,0.002075779],"category_scores_gemma":[0.002198383,0.0004542137,0.003127951,0.0004546191,0.001169891,0.00163166,0.000452812,0.003276352,0.0004587546],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001010018,"about_ca_system_score_gemma":0.001107329,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001359886,"about_ca_topic_score_gemma":0.002142758,"domain_scores_codex":[0.9991785,0.0003728746,0.00004861476,0.0001200261,0.0001061822,0.0001738274],"domain_scores_gemma":[0.9985793,0.0004445992,0.0004096115,0.0001217899,0.0001021914,0.0003425678],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.916632,0.00723965,0.0125437,0.0009093576,0.004839318,0.0001699168,0.0001771825,0.001136816,0.00409444,0.0001947987,0.00227888,0.04978411],"study_design_scores_gemma":[0.7891964,0.1533073,0.04849878,0.000146272,0.003643,0.0003080356,0.0001478373,0.0007142657,0.001031868,0.0004224851,0.002515712,0.00006800793],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988514,0.00785455,0.0002437273,0.0007414999,0.0001161267,0.0002879804,0.001198525,0.00003682944,0.001006844],"genre_scores_gemma":[0.9901932,0.003696457,0.0005158913,0.001033855,0.0002536683,0.0005987235,0.00250747,0.00001738364,0.001183369],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002877089,"threshold_uncertainty_score":0.01370353,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0121924784074163,"score_gpt":0.2549349209336827,"score_spread":0.2427424425262664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}