{"id":"W4416716313","doi":"10.1021/acs.bioconjchem.5c00494","title":"<sup>68</sup> Ga-Labeled Peptides Targeting Oxytocin Receptor in Breast Cancer Using Linchpin Chemistry for Tandem Peptide Cyclization and Radiometal Chelator Incorporation","year":2025,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Breast cancer; Oxytocin; Positron emission tomography; In vitro; Peptide; Molecular imaging; Chelation; Receptor; DOTA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002048903,0.0003594517,0.0004213409,0.00006868423,0.0002594537,0.0001098802,0.0002409964,0.0002408378,0.000119236],"category_scores_gemma":[0.0003775369,0.0003694425,0.0000984605,0.0005367891,0.0002298635,0.0002617024,0.0001546252,0.0002838174,0.000004688232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002125755,"about_ca_system_score_gemma":0.0001950579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006752902,"about_ca_topic_score_gemma":0.000001671182,"domain_scores_codex":[0.9978208,0.00005713355,0.0005844707,0.0009047067,0.0001578659,0.0004750233],"domain_scores_gemma":[0.9990945,0.0001570456,0.0003013006,0.0002209931,0.0001030647,0.000123047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001633991,0.00007662365,0.003632649,0.0005341605,0.00001306577,0.000004652803,0.00005622258,0.0007057023,0.9940826,0.00003089372,0.0003859072,0.0003141618],"study_design_scores_gemma":[0.001336323,0.00001924097,0.0007546769,0.0002605745,0.00003028771,0.0000169982,0.0001177295,0.01982295,0.9753563,0.0002065232,0.001706382,0.0003719598],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983325,0.0002105876,0.00006401035,0.0002510095,0.00007650939,0.000483406,0.0001646743,0.00008954741,0.0003277612],"genre_scores_gemma":[0.9974816,0.0002633124,0.0005850044,0.000361234,0.0003302353,0.0001148688,0.00007401282,0.00004863528,0.000741048],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01911725,"threshold_uncertainty_score":0.9998757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02053976383283135,"score_gpt":0.2750287743510406,"score_spread":0.2544890105182092,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}