{"id":"W4416723643","doi":"10.3390/nano15231771","title":"Therapeutic Potential of Nanoscale Metal–Organic Frameworks in Hepatocellular Carcinoma","year":2025,"lang":"en","type":"review","venue":"Nanomaterials","topic":"Metal-Organic Frameworks: Synthesis and Applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Photothermal therapy; Sonodynamic therapy; Drug delivery; Therapeutic modalities; Hepatocellular carcinoma; Targeted drug delivery; Cancer therapy; Drug; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001178177,0.0004243135,0.0004326793,0.0008446223,0.0001367646,0.0002751285,0.000267884,0.0004767817,0.001005758],"category_scores_gemma":[0.000104984,0.0001792775,0.000252803,0.0006162082,0.0001139551,0.0003248655,0.000253315,0.0004814521,0.0004294849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002650238,"about_ca_system_score_gemma":0.0002022106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005668355,"about_ca_topic_score_gemma":0.001011028,"domain_scores_codex":[0.9999588,0.00000609703,0.000003499233,0.000007885584,0.00001616217,0.00000765086],"domain_scores_gemma":[0.9999776,0.000008884009,0.000005043582,7.337715e-7,0.000004836107,0.000002866009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001042785,0.0001711292,0.0002109583,0.01974071,0.0001154416,0.0005092416,0.0000843068,0.001270666,0.04438975,0.007135268,0.01444735,0.9118209],"study_design_scores_gemma":[0.00002424156,0.0003331002,0.001306546,0.001200284,0.0001429241,0.00193852,0.00004580033,0.0006660012,0.01588439,0.001019779,0.9774067,0.0000316833],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001695568,0.9954614,0.0003384774,0.00009722113,0.0001072234,0.00000887019,0.00001999159,0.00001493426,0.002256303],"genre_scores_gemma":[0.01532403,0.9823794,0.0004751334,0.0001447837,0.0001058224,0.00001626473,0.00003870472,0.000002245326,0.001513607],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001005758,"threshold_uncertainty_score":0.003364623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02233411026016154,"score_gpt":0.2750361174143355,"score_spread":0.252702007154174,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}