{"id":"W4416733602","doi":"10.1093/ehjcr/ytaf607","title":"Transplanting the unexpected: a case report of a heart allograft with wild-type transthyretin cardiac amyloid","year":2025,"lang":"en","type":"article","venue":"European Heart Journal - Case Reports","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Libin Cardiovascular Institute of Alberta","funders":"","keywords":"Transthyretin; Cardiac amyloidosis; Amyloidosis; Amyloid (mycology); Heart failure; AL amyloidosis; Natural history; Heart transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007392376,0.002361551,0.001638112,0.002276035,0.003517398,0.003184529,0.001390963,0.005815946,0.002623254],"category_scores_gemma":[0.004036693,0.00143219,0.002042383,0.001161582,0.001719974,0.002778532,0.002075617,0.004955812,0.001061382],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001131424,"about_ca_system_score_gemma":0.0007614263,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001133667,"about_ca_topic_score_gemma":0.001377208,"domain_scores_codex":[0.9988306,0.0001725933,0.0001519964,0.0002905669,0.0001809644,0.0003731298],"domain_scores_gemma":[0.9959353,0.001090846,0.0008823517,0.0003923037,0.0002230752,0.00147605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00002182201,0.0000442886,0.004807063,0.00001512574,0.000007251841,0.993937,0.0002177973,0.00002913451,0.0003422935,0.00008244105,0.00009431203,0.0004013326],"study_design_scores_gemma":[0.000004205529,0.0000459236,0.001558753,0.00001002713,0.00000861151,0.9976718,0.0001244299,0.0001538972,0.0001622352,0.00006134963,0.0001925101,0.000006309027],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845638,0.003038694,0.003441307,0.002086318,0.0005874805,0.0001117595,0.0001051508,0.0001584927,0.005907019],"genre_scores_gemma":[0.995573,0.000674219,0.001210225,0.0007078174,0.000928157,0.00001628394,0.00004730651,0.00002536771,0.0008174884],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005815946,"threshold_uncertainty_score":0.008775651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01368925293843381,"score_gpt":0.277233548845318,"score_spread":0.2635442959068842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}