{"id":"W4416734638","doi":"10.1002/hem3.70248","title":"Patterns and safety of glucocorticosteroid use following CD19 CAR‐T therapy for large B‐cell lymphoma","year":2025,"lang":"en","type":"article","venue":"HemaSphere","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Cancer Institute; National Institutes of Health; Memorial Sloan-Kettering Cancer Center","keywords":"Corticosteroid; Hazard ratio; Cumulative dose; Lymphoma; Cytokine release syndrome; Cumulative incidence; Toxicity; Methylprednisolone; Prednisone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002653941,0.0001818544,0.0004463566,0.00006834121,0.00008273542,0.00003060895,0.00009851616,0.0001262424,0.0005956294],"category_scores_gemma":[0.00006904041,0.0001574864,0.0002399578,0.0001858896,0.00002612474,0.00008601666,0.00007382853,0.000096994,0.000003370545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008571297,"about_ca_system_score_gemma":0.0001532054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001557618,"about_ca_topic_score_gemma":0.0001044885,"domain_scores_codex":[0.9986376,0.00004990955,0.000342429,0.0003302196,0.0002523916,0.0003874945],"domain_scores_gemma":[0.9989272,0.000320116,0.00006408227,0.0004641994,0.0001113303,0.0001130285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00477338,0.001236731,0.4539907,0.001239863,0.0006027192,0.00007349811,0.0009916716,0.000001081341,0.4331224,0.0004764192,0.001850701,0.1016408],"study_design_scores_gemma":[0.07168373,0.00154495,0.2364938,0.001160795,0.0002930097,0.0000343148,0.001956712,0.0005905639,0.4764916,0.0003039771,0.2089031,0.0005434125],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923905,0.002079165,0.00166112,0.0002915946,0.0001490215,0.001400635,0.00005117751,0.00004192624,0.001934884],"genre_scores_gemma":[0.9787595,0.000744447,0.0005361276,0.0005797565,0.00006007864,0.00008573463,0.00003419461,0.00004367796,0.01915646],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2174969,"threshold_uncertainty_score":0.6521725,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02280704995492503,"score_gpt":0.3072871860336976,"score_spread":0.2844801360787725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}