{"id":"W4416738799","doi":"10.1007/s10571-025-01618-1","title":"Non-coding RNAs in Parkinson's Disease: Pathogenesis, Exosomes, and Therapeutic Horizons","year":2025,"lang":"en","type":"article","venue":"Cellular and Molecular Neurobiology","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"microRNA; Biomarker; Non-coding RNA; Disease; RNA interference; Parkinson's disease; Microvesicles","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001161104,0.0002151502,0.0001984234,0.0001307453,0.00007460589,0.00002448346,0.000124371,0.0001667309,0.000004141879],"category_scores_gemma":[0.00003246977,0.0002218867,0.00006913226,0.0001297113,0.0001528801,0.000003001222,0.0001822588,0.00009398899,0.000001391553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001070679,"about_ca_system_score_gemma":0.00007469484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005769339,"about_ca_topic_score_gemma":0.000006572889,"domain_scores_codex":[0.9987362,0.0001414416,0.0002010065,0.0005894098,0.00004418176,0.0002877682],"domain_scores_gemma":[0.9994596,0.00001463628,0.00005086582,0.0003369164,0.00002792421,0.0001100194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006865001,0.00004047552,0.01028365,0.00005699394,0.00003429901,0.00004879056,0.000008536262,0.00002308069,0.9863285,0.00067502,0.00006565177,0.002366322],"study_design_scores_gemma":[0.001327278,0.0001606801,0.1454781,0.00005638775,0.0001124103,0.00002113545,0.00002317,0.000333629,0.7760437,0.000776856,0.07521892,0.0004478171],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9746722,0.01798936,0.006392343,0.0002854202,0.0001475252,0.0003168638,0.00001456621,0.00001310181,0.0001685971],"genre_scores_gemma":[0.9976856,0.001172616,0.00008252139,0.0007079127,0.00003509086,0.00003868942,0.0001343182,0.0000239891,0.0001193255],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2102849,"threshold_uncertainty_score":0.9048278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005634444557287947,"score_gpt":0.2205905664436666,"score_spread":0.2149561218863786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}