{"id":"W4416746001","doi":"10.1016/j.fsi.2025.111047","title":"An analog of Clarias gariepinus Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP-38) contributes to immune homeostasis and defences against Vibrio parahaemolyticus in Litopenaeus vannamei","year":2025,"lang":"en","type":"article","venue":"Fish & Shellfish Immunology","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"International Development Research Centre","keywords":"Vibrio parahaemolyticus; Antimicrobial peptides; Antimicrobial; Shellfish; Shrimp; Litopenaeus; Hemolymph; Antibiotics; Vibrio","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007286698,0.0003236447,0.0001640612,0.0001239013,0.00008250763,0.0001699706,0.0001719308,0.0002845592,0.001235708],"category_scores_gemma":[0.0001250169,0.00008119069,0.0001616754,0.00005870687,0.0002252256,0.0001750345,0.0002136505,0.0004073919,0.0001397836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001562895,"about_ca_system_score_gemma":0.0001238151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004507416,"about_ca_topic_score_gemma":0.000542747,"domain_scores_codex":[0.9999205,0.000008895472,0.000006738673,0.00002120516,0.00002444815,0.00001819357],"domain_scores_gemma":[0.9999391,0.000007515192,0.0000255447,0.000004231571,0.000005618863,0.00001800232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001551914,0.00001423033,0.0001782959,0.00005583512,0.000003168018,0.00006489557,0.000007562244,0.00005785677,0.9983007,0.00002352371,0.00001195429,0.00112672],"study_design_scores_gemma":[0.00005897683,0.003442735,0.01462286,0.00002716125,0.00005014554,0.0009977767,0.0001211957,0.0008119042,0.9742174,0.00007924114,0.005553758,0.00001671391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973782,0.001243389,0.0005352158,0.00007229597,0.00003125057,0.00002027344,0.0001400851,0.00001358519,0.0005655753],"genre_scores_gemma":[0.9962898,0.0007226035,0.001162164,0.00007435226,0.00001087618,0.00002846795,0.0002281332,0.000004039262,0.001479494],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001235708,"threshold_uncertainty_score":0.004133821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006893167823133623,"score_gpt":0.2439772774555432,"score_spread":0.2370841096324096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}