{"id":"W4416759013","doi":"10.1016/j.brs.2025.102994","title":"Open letter on intervention regimes and adverse events in focused ultrasound for neuromodulation","year":2025,"lang":"en","type":"letter","venue":"Brain stimulation","topic":"Ultrasound and Hyperthermia Applications","field":"Engineering","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; Sunnybrook Health Science Centre","funders":"","keywords":"Neuromodulation; Focused ultrasound; Adverse effect; Intervention (counseling); Psychological intervention","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001574911,0.0004844237,0.00103788,0.0005302565,0.002506261,0.002487745,0.001013636,0.0346714,0.005906772],"category_scores_gemma":[0.02017836,0.0003426008,0.001070607,0.0004238494,0.001382934,0.001389713,0.0006614509,0.01571649,0.003270359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003594639,"about_ca_system_score_gemma":0.00225382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002514401,"about_ca_topic_score_gemma":0.005174686,"domain_scores_codex":[0.9983149,0.0006045887,0.0002131658,0.0001770423,0.0004775361,0.0002127487],"domain_scores_gemma":[0.9936219,0.004163952,0.0006245325,0.0001793566,0.0007534802,0.0006567889],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003261481,0.000177536,0.002076341,0.0001128772,0.00004494475,0.02470342,0.0002168134,0.0001762177,0.000418958,0.003111808,0.9470701,0.02156486],"study_design_scores_gemma":[0.000445971,0.0003360619,0.003793231,0.0005262464,0.0001262419,0.02973423,0.0005483652,0.00174561,0.0006356411,0.01480343,0.9472088,0.00009628409],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.003540531,0.002278276,0.0004186263,0.9518475,0.02584417,0.00005018897,0.0001324666,0.00008445576,0.01580384],"genre_scores_gemma":[0.02388308,0.00235875,0.0008065201,0.869953,0.0850178,0.0001225073,0.00007763331,0.00006472029,0.01771599],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.0346714,"threshold_uncertainty_score":0.02608103,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02098118964189806,"score_gpt":0.2709432822189589,"score_spread":0.2499620925770609,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}