{"id":"W4416807094","doi":"10.1016/j.tibtech.2025.11.001","title":"Glutaraldehyde-induced porcine model mimics human chronic wounds: insights into pathophysiology and therapeutic applications","year":2025,"lang":"en","type":"article","venue":"Trends in biotechnology","topic":"Wound Healing and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; McGill University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Chronic wound; Pathophysiology; Transcriptome; Extracellular matrix; Human disease; Zebrafish; Animal model; Animal studies","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005627652,0.000200404,0.0004075388,0.0009231461,0.0001488148,0.000005966163,0.0001222935,0.000605686,0.00001076571],"category_scores_gemma":[0.000006833571,0.0001712021,0.00004567881,0.0007159314,0.0002218556,0.00001845706,0.00008027488,0.0004410039,0.000008143496],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003283317,"about_ca_system_score_gemma":0.0001051414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000174953,"about_ca_topic_score_gemma":0.0004683602,"domain_scores_codex":[0.9988375,0.00002486411,0.0002974451,0.0004558853,0.0000594501,0.0003248543],"domain_scores_gemma":[0.9993024,0.00002540766,0.00006169754,0.0005325766,0.00002584877,0.00005203257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001286917,0.0008724137,0.003289804,0.0001705147,0.0002638074,0.00004369432,0.0004861531,0.00008066979,0.4135862,0.1237328,0.00008895612,0.4572563],"study_design_scores_gemma":[0.02028137,0.004653335,0.07602254,0.0005610865,0.0009770242,0.0001153823,0.0003951486,0.04159826,0.07818379,0.7532094,0.02278554,0.001217182],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827962,0.004523176,0.0007126867,0.01027404,0.00005105641,0.0002885971,0.000002349571,0.0002333731,0.001118556],"genre_scores_gemma":[0.9968134,0.0006180516,0.001000314,0.0005911982,0.00003220776,0.000176002,0.00006378061,0.00001706814,0.0006880091],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6294765,"threshold_uncertainty_score":0.6981421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02380369933723844,"score_gpt":0.3425757741836489,"score_spread":0.3187720748464105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}