{"id":"W4416809030","doi":"10.1016/j.vaccine.2025.128007","title":"Development of a recombinant fusion protein subunit vaccine comprising two truncated proteins effectively protects largemouth bass against infectious spleen and kidney necrosis virus infection","year":2025,"lang":"en","type":"article","venue":"Vaccine","topic":"Aquaculture disease management and microbiota","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Key Technologies Research and Development Program of Guangzhou; Special Project for Research and Development in Key areas of Guangdong Province; South China Agricultural University; National Natural Science Foundation of China; Canadian Society for Molecular Biosciences","keywords":"Spleen; Immunogenicity; Virus; Capsid; Fusion protein; Antibody; Recombinant DNA; Protein subunit","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002082539,0.0005266686,0.0002959867,0.0001665068,0.0001580612,0.0003265232,0.0002612673,0.0004058398,0.0008029396],"category_scores_gemma":[0.0001515328,0.0001663476,0.0003192431,0.0001046752,0.0002702021,0.0002924783,0.0002301468,0.0009536594,0.0002474288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002996543,"about_ca_system_score_gemma":0.0002697372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004580862,"about_ca_topic_score_gemma":0.0005109534,"domain_scores_codex":[0.9998703,0.00001919031,0.00001251179,0.00002742266,0.00003267406,0.00003784763],"domain_scores_gemma":[0.9999115,0.00001565385,0.00002668123,0.000009360179,0.00001425474,0.00002240624],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001619744,0.00007781726,0.0002486064,0.00002692953,0.000007157901,0.00003642884,0.00001464289,0.0001902517,0.9976835,0.00007315235,0.0000429963,0.001436506],"study_design_scores_gemma":[0.00008238867,0.002202376,0.003261548,0.00001134878,0.00006759859,0.0003842555,0.00007070308,0.00223512,0.9888114,0.00006947681,0.002795195,0.000008740949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933606,0.0003344592,0.005358686,0.00009779094,0.0000567301,0.00006833331,0.0001591675,0.00004531708,0.0005190149],"genre_scores_gemma":[0.9936634,0.0002844408,0.003824932,0.00006248759,0.00001453861,0.00004117353,0.0006278852,0.00001152148,0.001469529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008029396,"threshold_uncertainty_score":0.002686083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006984501795464476,"score_gpt":0.2294666210633471,"score_spread":0.2224821192678826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}