{"id":"W4416840488","doi":"10.1021/acs.orglett.5c04616","title":"Glyoxylate Sulfonyl Hydrazone Enables a Scalable Approach to Reformatsky-Type Products from Aliphatic Alcohols via Photocatalytic HAT","year":2025,"lang":"en","type":"article","venue":"Organic Letters","topic":"Sulfur-Based Synthesis Techniques","field":"Chemistry","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"HORIZON EUROPE European Innovation Council; H2020 Marie Skłodowska-Curie Actions; Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"Sulfonyl; Photocatalysis; Hydrazone; Hydrazide; Glyoxylate cycle; Catalysis; Decomposition","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001073751,0.0003509503,0.0001212949,0.00009032173,0.00009811419,0.0001354659,0.0001751332,0.0002229478,0.001581654],"category_scores_gemma":[0.00008759174,0.0001113715,0.0001336442,0.00008552084,0.0001915889,0.0002857396,0.0002535213,0.000513308,0.0005609294],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001918741,"about_ca_system_score_gemma":0.0001914074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003836874,"about_ca_topic_score_gemma":0.001057051,"domain_scores_codex":[0.9999373,0.000007100153,0.00000410424,0.00001257728,0.00001845714,0.00002051874],"domain_scores_gemma":[0.9999608,0.00000570456,0.00001321309,0.000007986409,0.000005158007,0.00000712673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006332729,0.00002094749,0.00009872936,0.0001055601,0.000008126807,0.0002128619,0.00004447849,0.0003426173,0.9910105,0.001310555,0.0003676439,0.006414631],"study_design_scores_gemma":[0.000004789977,0.0001153889,0.0002030046,0.000002585044,0.000004861878,0.000137276,0.00001242661,0.000465675,0.9946067,0.00008573897,0.004357563,0.000004068439],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9195336,0.003045181,0.05852241,0.0007227823,0.0001251392,0.0001212317,0.0006564096,0.0008972398,0.01637597],"genre_scores_gemma":[0.9904464,0.0008627785,0.005813565,0.00004615588,0.00001420052,0.0000167265,0.0001366709,0.00002639713,0.002637105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001581654,"threshold_uncertainty_score":0.005291104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01140941693951618,"score_gpt":0.2225506750239707,"score_spread":0.2111412580844545,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}