{"id":"W4416842599","doi":"10.1016/j.exphem.2025.105133","title":"3192 – MODELING CLONAL HEMATOPOIESIS DUE TO CHROMOSOME 13Q DELETION IN HUMAN HEMATOPOIETIC STEM CELLS","year":2025,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Stem Cell Network; Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Haematopoiesis; Myeloid; Stem cell; Monocyte; Macrophage; Myeloid leukemia; Transgene; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001459814,0.0002696354,0.0001457103,0.0001635214,0.0001100906,0.0002512606,0.0003448535,0.0003363047,0.003206135],"category_scores_gemma":[0.0003071817,0.0001604145,0.0002619305,0.0001739083,0.0001792632,0.0001214575,0.0001695455,0.0002026736,0.0002779557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003453403,"about_ca_system_score_gemma":0.00039446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006203505,"about_ca_topic_score_gemma":0.002986992,"domain_scores_codex":[0.9999437,0.00001392657,0.000002000695,0.000009690375,0.00002154555,0.000009086646],"domain_scores_gemma":[0.9999379,0.00002808258,0.00001104908,0.000007585952,0.0000102753,0.000005054606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.000101566,0.00007782962,0.002606947,0.00002791321,0.00001732025,0.0002414294,0.00003795374,0.9329727,0.05266804,0.00693843,0.0004195713,0.003890167],"study_design_scores_gemma":[0.00002458018,0.00006027268,0.000964258,0.000002111868,0.000007420827,0.00003975859,0.00001436688,0.9801984,0.01645824,0.001012658,0.00121488,0.000003016935],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9480546,0.0000768961,0.03961401,0.0001319328,0.00002960648,0.00005165062,0.0006798796,0.0001892446,0.01117214],"genre_scores_gemma":[0.9837716,0.00006531231,0.01018791,0.00003069054,0.000004079,0.00003956971,0.0004805233,0.00004026032,0.005379979],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006203505,"threshold_uncertainty_score":0.01233476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02315544602643023,"score_gpt":0.3361266793464209,"score_spread":0.3129712333199907,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}