{"id":"W4416848478","doi":"10.1182/bloodadvances.2025017934","title":"American Society of Hematology 2025 guidelines for treating newly diagnosed acute myeloid leukemia in older adults","year":2025,"lang":"en","type":"article","venue":"Blood Advances","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University Hospital Foundation","funders":"","keywords":"Hematology; Myeloid leukemia; Guideline; Transplantation; Population; Hematopoietic stem cell transplantation; Venetoclax; Induction chemotherapy; Gemtuzumab ozogamicin; Azacitidine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008505451,0.001234622,0.001722785,0.004863922,0.001167839,0.003099514,0.003216698,0.004670745,0.01498807],"category_scores_gemma":[0.02645637,0.000567972,0.002354748,0.004548782,0.0007253146,0.0016141,0.002283082,0.007466846,0.01044892],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004518085,"about_ca_system_score_gemma":0.02011334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01331276,"about_ca_topic_score_gemma":0.02406536,"domain_scores_codex":[0.9890432,0.004072122,0.003017219,0.0003149522,0.003044348,0.0005080029],"domain_scores_gemma":[0.9767297,0.003986932,0.003176481,0.0004435687,0.01396446,0.001698893],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004325114,0.00005978147,0.0007066193,0.001882111,0.00004989078,0.0001414661,0.000124656,0.0002486132,0.0001675494,0.0023149,0.8525762,0.1416849],"study_design_scores_gemma":[0.0001006307,0.0000385163,0.001418192,0.007067942,0.00009414754,0.0003454304,0.00008299225,0.0001835786,0.00008133513,0.001780462,0.9887887,0.00001817498],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.002566927,0.3093798,0.0183604,0.3758647,0.04370839,0.007006614,0.01773154,0.001520121,0.2238615],"genre_scores_gemma":[0.022899,0.4266063,0.1433795,0.2085574,0.02246162,0.01730548,0.05741868,0.0005747272,0.1007973],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.01498807,"threshold_uncertainty_score":0.05014008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02068913321019753,"score_gpt":0.3621638064432042,"score_spread":0.3414746732330067,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}