{"id":"W4416866141","doi":"10.1681/asn.2025bs6p5t79","title":"Terminal Complement Proteins Dominate Chronic Active Antibody-Mediated Rejection","year":2025,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Terminal (telecommunication); Complement (music); Complement system; Amino terminal; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038628,0.0001588361,0.0005970407,0.0000974342,0.0001888889,0.000005493679,0.000527181,0.00007212334,0.0001842671],"category_scores_gemma":[0.00005587825,0.0001128886,0.0005366486,0.0003617917,0.001066142,0.00006185983,0.0002181332,0.0003725578,0.000009744857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002725687,"about_ca_system_score_gemma":0.0003671593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001853417,"about_ca_topic_score_gemma":0.00002543394,"domain_scores_codex":[0.9982679,0.000538398,0.0006556291,0.000158208,0.00008301254,0.0002968604],"domain_scores_gemma":[0.9974539,0.0002838337,0.001719424,0.0002916974,0.0002319211,0.00001916769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006626974,0.0001977489,0.003792502,0.00005241925,0.001002162,0.000001897408,0.0002890459,0.00001902792,0.9443941,0.00007660402,0.04547288,0.004038947],"study_design_scores_gemma":[0.005892275,0.003229186,0.6671937,0.000431087,0.0006850069,0.0004278577,0.004284734,0.00007656615,0.09988152,0.0006452223,0.2169685,0.000284299],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992115,0.0009460945,0.00109846,0.004749021,0.0005048082,0.0004266762,0.0000478583,0.00001315938,0.00009898897],"genre_scores_gemma":[0.9976031,0.0001492807,0.0003471975,0.001534948,0.00008749965,0.00001221227,0.00001051982,0.000008643926,0.000246641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8445125,"threshold_uncertainty_score":0.4603464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01132026609775504,"score_gpt":0.2981078132000571,"score_spread":0.2867875471023021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}