{"id":"W4416890315","doi":"10.1093/ismejo/wraf266","title":"Milk IgA promotes symbionts and limits pathobionts in the early life gut","year":2025,"lang":"en","type":"article","venue":"The ISME Journal","topic":"Infant Nutrition and Health","field":"Nursing","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Colonization; Immunoglobulin A; Secretory IgA; Antibody; Gut flora; Escherichia coli; Proteus; Bacteria; Microbiome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003280168,0.0003311918,0.0003363017,0.0003441661,0.0002611868,0.0007235596,0.0002536127,0.000487334,0.0008342416],"category_scores_gemma":[0.0005121962,0.0001671694,0.0002266398,0.0001139953,0.0003949685,0.0003467714,0.0008041537,0.000676733,0.000325052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003517337,"about_ca_system_score_gemma":0.0004665533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008003722,"about_ca_topic_score_gemma":0.001251149,"domain_scores_codex":[0.9997668,0.00004899074,0.000009991636,0.00004830159,0.00005560459,0.00007029254],"domain_scores_gemma":[0.9997341,0.00003608256,0.00006895628,0.00002216872,0.0000385459,0.0001001231],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003910176,0.00006271544,0.01186744,0.0001585224,0.00001668568,0.0003597014,0.0002805602,0.0001219997,0.9627166,0.0009573471,0.0002592019,0.02280822],"study_design_scores_gemma":[0.00004292636,0.002784986,0.4304302,0.0002830277,0.00009834312,0.001840024,0.001496376,0.001990767,0.5306439,0.002952228,0.02738609,0.00005094559],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840965,0.007995369,0.003337555,0.0004526681,0.00008763625,0.00001459659,0.000109787,0.0001368763,0.003768957],"genre_scores_gemma":[0.9922841,0.002160868,0.00306685,0.0001571147,0.00003956764,0.00001534155,0.00007134895,0.00002450687,0.00218032],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008342416,"threshold_uncertainty_score":0.002790868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02271300953382039,"score_gpt":0.3004925239264043,"score_spread":0.2777795143925839,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}