{"id":"W4416905352","doi":"10.1080/21505594.2025.2589554","title":"Genome-scale CRISPR screen identifies host factors associated with bovine parainfluenza virus 3 infection","year":2025,"lang":"en","type":"article","venue":"Virulence","topic":"Respiratory viral infections research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Agriculture","funders":"National Key Research and Development Program of China","keywords":"Gene; Gene knockdown; Viral replication; Virus; Host factor; CRISPR; Pathogen; Host (biology)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002903053,0.0004369858,0.0007071047,0.0004108793,0.0002788138,0.0005343625,0.0002965845,0.0004779092,0.001317698],"category_scores_gemma":[0.0003740416,0.0002069615,0.0004745767,0.0002648243,0.0002140722,0.0001506468,0.0004026516,0.000590961,0.0004872564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003985761,"about_ca_system_score_gemma":0.0003857843,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001883832,"about_ca_topic_score_gemma":0.003289322,"domain_scores_codex":[0.9996722,0.00003137375,0.00002847989,0.00008451352,0.0001194191,0.00006401623],"domain_scores_gemma":[0.9998332,0.00004733929,0.0000468838,0.00001597868,0.00002139787,0.00003508391],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001113893,0.00002701577,0.001177163,0.0001275431,0.00001819754,0.0002568318,0.00003234141,0.000210798,0.9947276,0.0001018895,0.0002592721,0.002950137],"study_design_scores_gemma":[0.00007753283,0.0006993992,0.04049038,0.00008551979,0.0002902886,0.002365031,0.0002939663,0.0100653,0.9219994,0.0002373002,0.02332223,0.00007359208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.965007,0.004334423,0.01888086,0.0002778964,0.0001071863,0.0001817939,0.00652296,0.0009707643,0.003717083],"genre_scores_gemma":[0.9665086,0.002406184,0.01952734,0.0002735138,0.00001256117,0.0001464075,0.007286865,0.0001942405,0.003644432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001883832,"threshold_uncertainty_score":0.004408181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0486538936784215,"score_gpt":0.3558134530753286,"score_spread":0.3071595593969071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}