{"id":"W4416920861","doi":"10.1016/j.thromres.2025.109556","title":"Suboptimal management of cancer-associated thrombotic microangiopathies in newly diagnosed and known cancers: A 15-year provincial retrospective cohort study","year":2025,"lang":"en","type":"letter","venue":"Thrombosis Research","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; University of British Columbia","funders":"","keywords":"Retrospective cohort study; Thrombotic microangiopathy; Cohort; Cohort study; Young adult; Therapeutic plasma exchange","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001966765,0.0005441232,0.001700418,0.001106147,0.0003289292,0.00007500028,0.0009404282,0.0007158339,0.001128051],"category_scores_gemma":[0.0002396472,0.0005413903,0.0001852323,0.001228371,0.0008372813,0.00009749016,0.00120878,0.002281533,0.00005078964],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002582685,"about_ca_system_score_gemma":0.0007852563,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.05018265,"about_ca_topic_score_gemma":0.01592585,"domain_scores_codex":[0.9936079,0.002284314,0.0009351406,0.001314127,0.0005842664,0.001274233],"domain_scores_gemma":[0.9974446,0.0007156249,0.0003510418,0.0008691801,0.0005834502,0.00003611252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001315723,0.0006457003,0.6216765,0.000866559,0.002966794,0.000125642,0.000878702,0.000002994627,0.0005807649,0.00003503429,0.3719547,0.0001350099],"study_design_scores_gemma":[0.003726789,0.0008054443,0.9858829,0.002208818,0.0005767517,8.626395e-7,0.002662321,0.000002801995,0.000287734,0.00008822367,0.003300035,0.0004573532],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9716457,0.005361536,7.346216e-7,0.01137105,0.0006979225,0.007823016,0.001375519,0.00008567311,0.001638836],"genre_scores_gemma":[0.9904066,0.001797305,0.00001771652,0.001330238,0.0002044709,0.002684253,0.0005190748,0.00007575125,0.002964625],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3686547,"threshold_uncertainty_score":0.9997851,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04237085749978217,"score_gpt":0.3614463428513961,"score_spread":0.3190754853516139,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}