{"id":"W4416930951","doi":"10.1055/s-0045-1812908","title":"AHOD2131: A Randomized Phase 3 Response-Adapted Trial Comparing Standard Therapy to Immuno-oncology for Children &amp; Adults with Newly Diagnosed Stage I and II Hodgkin Lymphoma","year":2025,"lang":"","type":"article","venue":"Klinische Pädiatrie","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children's Hospital of Western Ontario; London Health Sciences Centre; Western University","funders":"","keywords":"Stage (stratigraphy); Hodgkin lymphoma; Randomized controlled trial; Radiation therapy; Lymphoma; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001444666,0.001271852,0.002550709,0.0003846331,0.0004640715,0.001176561,0.0009212756,0.001623491,0.00816856],"category_scores_gemma":[0.00139515,0.0004500274,0.00200929,0.0004309879,0.0009323717,0.0009375031,0.0006053132,0.003668653,0.001085355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008222312,"about_ca_system_score_gemma":0.001089718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001022148,"about_ca_topic_score_gemma":0.002473717,"domain_scores_codex":[0.9993876,0.0003409011,0.0000276868,0.0000974988,0.00003568357,0.0001105947],"domain_scores_gemma":[0.999283,0.0001849045,0.0001292685,0.00006535587,0.00003577052,0.0003017357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9558263,0.006081049,0.001074034,0.0007857476,0.001458141,0.00004612535,0.00005208084,0.0007254513,0.002012469,0.000218361,0.002331126,0.02938906],"study_design_scores_gemma":[0.9642794,0.03188984,0.002026458,0.00002740012,0.0002911466,0.00003295854,0.00001625037,0.0002639421,0.0001459991,0.0001602907,0.0008561534,0.00001020635],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9782192,0.006993707,0.0009217609,0.001602074,0.0008368962,0.004741799,0.002582883,0.0002132466,0.003888371],"genre_scores_gemma":[0.9772633,0.002770061,0.002505225,0.003750658,0.0005635612,0.005228285,0.003156749,0.00004613064,0.004716119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00816856,"threshold_uncertainty_score":0.02732652,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02291533433000346,"score_gpt":0.3364854965179532,"score_spread":0.3135701621879498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}