{"id":"W4416947030","doi":"10.1021/acs.analchem.5c04928","title":"Toward Fully Integrated Microneedle Sensors: Advances and Challenges in Personalized Health Monitoring and Drug Delivery","year":2025,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"National Natural Science Foundation of China; Natural Science Foundation of Guangxi Zhuang Autonomous Region","keywords":"Drug delivery; Personalized medicine; Drug; Targeted drug delivery; Biocompatible material","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002683615,0.0007546727,0.0009897188,0.0004883182,0.0002125865,0.002363519,0.001136321,0.002089557,0.001994696],"category_scores_gemma":[0.002487812,0.0004906555,0.0004269565,0.0004640801,0.0007690591,0.004020612,0.001263675,0.002267228,0.001240084],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008636374,"about_ca_system_score_gemma":0.001101749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000742052,"about_ca_topic_score_gemma":0.001242106,"domain_scores_codex":[0.9987709,0.0002211213,0.00006525719,0.0002794185,0.0005539169,0.0001094301],"domain_scores_gemma":[0.998316,0.0007121325,0.0001842483,0.00009510837,0.0005953873,0.00009708527],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000213782,0.000178177,0.001067222,0.002185095,0.00009000166,0.0001493922,0.0002640066,0.002268685,0.6948287,0.0241717,0.006559282,0.2680239],"study_design_scores_gemma":[0.00004088544,0.001109822,0.002359556,0.0005154865,0.0001408058,0.001061949,0.0003425158,0.04346834,0.6779411,0.02277102,0.2501073,0.0001412973],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.05921094,0.2168278,0.6923534,0.01416115,0.001513828,0.0003277781,0.0008295801,0.001596288,0.01317936],"genre_scores_gemma":[0.2756398,0.1428663,0.5539119,0.008869996,0.0009647876,0.0003558884,0.0009787694,0.0002402816,0.01617237],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.002683615,"threshold_uncertainty_score":0.01419246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1180019818333234,"score_gpt":0.4173557921352334,"score_spread":0.29935381030191,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}