{"id":"W4416974191","doi":"10.1016/j.fertnstert.2025.07.333","title":"NON-INVASIVE MISCARRIAGE TESTING USING CELL-FREE DNA: FACTORS CONTRIBUTING TO NON-INFORMATIVE RESULTS","year":2025,"lang":"en","type":"article","venue":"Fertility and Sterility","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Amorfix (Canada)","funders":"","keywords":"Miscarriage; Pregnancy; Abortion; MEDLINE; Parity (physics)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02217441,0.0007084831,0.0007203906,0.002566106,0.0006827107,0.001577355,0.001429803,0.001259407,0.00253279],"category_scores_gemma":[0.09437902,0.0004002418,0.000476547,0.001575013,0.001957219,0.0008945837,0.0008207995,0.001219745,0.0008240014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005091463,"about_ca_system_score_gemma":0.0009646992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001090158,"about_ca_topic_score_gemma":0.0009205868,"domain_scores_codex":[0.9636661,0.01632264,0.002646775,0.002330718,0.01384514,0.001188597],"domain_scores_gemma":[0.8187259,0.1567237,0.008176845,0.007169436,0.008051007,0.001153138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002050504,0.0009905191,0.7666643,0.0008501293,0.0002450183,0.005744383,0.001971871,0.001460012,0.1102943,0.00302501,0.00119169,0.1055123],"study_design_scores_gemma":[0.00007291269,0.003840921,0.5744671,0.0004892912,0.001002362,0.046823,0.001958569,0.01712972,0.3357063,0.004411927,0.01397281,0.0001251336],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.92327,0.01072954,0.05253357,0.001643064,0.0002361532,0.0004229301,0.000454367,0.0003367504,0.01037352],"genre_scores_gemma":[0.9868129,0.001253498,0.009783249,0.0003431486,0.000105591,0.0001243083,0.000251436,0.00005846973,0.001267461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02217441,"threshold_uncertainty_score":0.1172708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01752529223734763,"score_gpt":0.2800586781731662,"score_spread":0.2625333859358186,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}