{"id":"W4416976608","doi":"10.1021/acs.jafc.5c10821","title":"Investigation of a Neuroprotective Peptide from Round Scad ( <i>Decapterus maruadsi</i> ): Bioactivity Validation, Gastrointestinal Digestion Stability, and Structure–Activity Relationship Analysis","year":2025,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Protein Hydrolysis and Bioactive Peptides","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Agriculture","funders":"Wuhan Polytechnic University; Natural Science Foundation of Hubei Province","keywords":"Neuroprotection; Peptide; Scad; Oxidative stress; In vivo; Caco-2; Biological activity; Digestion (alchemy); Neuropeptide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001196398,0.0002576782,0.000165762,0.0002087805,0.00009636726,0.0001480875,0.0001123049,0.0001853927,0.0006846006],"category_scores_gemma":[0.0001066727,0.00007051422,0.0002003761,0.0001272689,0.0001097614,0.0002105239,0.00009727269,0.0001951647,0.0001461752],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001217942,"about_ca_system_score_gemma":0.00008610545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002446332,"about_ca_topic_score_gemma":0.0003148636,"domain_scores_codex":[0.9999623,0.000003817956,0.000002849515,0.00001090907,0.00001364227,0.000006484932],"domain_scores_gemma":[0.9999307,0.00001041855,0.00002674214,0.000004788283,0.00001333908,0.0000139492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005161777,0.000008902185,0.0001608038,0.0000424221,0.000004405581,0.00003402962,0.000007734632,0.00009115228,0.9977019,0.00002042361,0.00001083428,0.001865776],"study_design_scores_gemma":[0.000007568913,0.0004413584,0.004199524,0.000005200302,0.00001632895,0.0001864159,0.00001988745,0.001626362,0.9921394,0.00003138625,0.001320616,0.000006025596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945431,0.001014376,0.003502439,0.00004652633,0.000009493131,0.00003771782,0.0002125158,0.00003322823,0.0006005726],"genre_scores_gemma":[0.986198,0.0009031715,0.01070495,0.00004004111,0.000008239783,0.00003662309,0.0004437211,0.00001521495,0.001649962],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006846006,"threshold_uncertainty_score":0.002290189,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01164183840858098,"score_gpt":0.2112439581482432,"score_spread":0.1996021197396622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}