{"id":"W4416995933","doi":"10.1158/2159-8290.cd-25-1101","title":"A High-Fiber, Plant-Based Diet in Myeloma Precursor Disorders: Results from the NUTRIVENTION Clinical Trial and Preclinical Vk*MYC Model","year":2025,"lang":"en","type":"article","venue":"Cancer Discovery","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"NextGenerationEU; National Cancer Institute; National Heart, Lung, and Blood Institute; American Society of Hematology; Tow Foundation; Paula and Rodger Riney Foundation; Fondazione AIRC per la ricerca sul cancro ETS; Allen Foundation; Sylvester Comprehensive Cancer Center, University of Miami Health Systems; International Myeloma Society","keywords":"Multiple myeloma; Immune system; Clinical trial; Body mass index; Microbiome; Immunity; Weight loss; Diabetes mellitus; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0113459,0.0005259833,0.001350469,0.0003342802,0.0005986194,0.001726591,0.001256544,0.004548164,0.004103159],"category_scores_gemma":[0.0155332,0.0002347832,0.00175993,0.0005396951,0.001152539,0.001282291,0.001085875,0.009319882,0.001256087],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001077702,"about_ca_system_score_gemma":0.002718638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002612117,"about_ca_topic_score_gemma":0.005931132,"domain_scores_codex":[0.9969312,0.001987587,0.0001785791,0.000284977,0.0004507781,0.0001668192],"domain_scores_gemma":[0.9865023,0.009562592,0.0007893473,0.0005023837,0.001863101,0.0007801831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.07091141,0.001606471,0.003468969,0.006679856,0.004053903,0.0006828379,0.0007724668,0.0004029689,0.00603608,0.006366931,0.5734651,0.3255529],"study_design_scores_gemma":[0.1270905,0.03261246,0.03349692,0.01874693,0.01468578,0.0007212528,0.001036138,0.001933262,0.00909442,0.02269282,0.7373855,0.0005040537],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.0625777,0.1958356,0.003466188,0.6694618,0.04252946,0.00129167,0.005970112,0.0005012805,0.01836623],"genre_scores_gemma":[0.2104854,0.1550407,0.005773157,0.5474274,0.05229943,0.004187219,0.00328217,0.0004448483,0.0210597],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.0113459,"threshold_uncertainty_score":0.06000364,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07918418177968839,"score_gpt":0.4054067463110885,"score_spread":0.3262225645314001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}