{"id":"W4416995933","doi":"10.1158/2159-8290.cd-25-1101","title":"A High-Fiber, Plant-Based Diet in Myeloma Precursor Disorders: Results from the NUTRIVENTION Clinical Trial and Preclinical Vk*MYC Model","year":2025,"lang":"en","type":"article","venue":"Cancer Discovery","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"NextGenerationEU; National Cancer Institute; National Heart, Lung, and Blood Institute; American Society of Hematology; Tow Foundation; Paula and Rodger Riney Foundation; Fondazione AIRC per la ricerca sul cancro ETS; Allen Foundation; Sylvester Comprehensive Cancer Center, University of Miami Health Systems; International Myeloma Society","keywords":"Multiple myeloma; Immune system; Clinical trial; Body mass index; Microbiome; Immunity; Weight loss; Diabetes mellitus; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005439497,0.0002074578,0.0005068533,0.00008414427,0.00008711193,0.00007021915,0.0001598275,0.0001637454,0.00002379673],"category_scores_gemma":[0.0007214487,0.0001363473,0.0002020563,0.0002041085,0.0002812516,0.000175108,0.0001058847,0.0004428472,0.000009808971],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001646444,"about_ca_system_score_gemma":0.0007672783,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002695864,"about_ca_topic_score_gemma":0.004177961,"domain_scores_codex":[0.9976595,0.0003001952,0.0007373985,0.0006440741,0.0003173262,0.0003415089],"domain_scores_gemma":[0.9972807,0.001906616,0.0001395229,0.000498454,0.00003665069,0.000138062],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7055131,0.002817986,0.1293186,0.0001154618,0.0006299076,0.00004708661,0.0001186107,0.001018064,0.00002854753,0.000261673,0.0118665,0.1482645],"study_design_scores_gemma":[0.4462098,0.002456825,0.4846855,0.00193207,0.0004828321,5.786773e-7,0.0001010225,0.0571658,0.0002370512,0.003162442,0.003253657,0.0003123666],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986792,0.001974155,0.0008126445,0.005710965,0.0004844695,0.001975817,0.001785419,0.0000346864,0.0004298711],"genre_scores_gemma":[0.9938118,0.002473672,0.0003459639,0.0004001969,0.0003348987,0.000468361,0.0006821566,0.00001804173,0.001464942],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3553669,"threshold_uncertainty_score":0.5560083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07918418177968839,"score_gpt":0.4054067463110885,"score_spread":0.3262225645314001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}