{"id":"W4417002206","doi":"10.1182/blood-2025-3547","title":"Evaluating targeted long-read sequencing as a diagnostic tool for burkitt lymphoma","year":2025,"lang":"en","type":"article","venue":"Blood","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Spinal Cord Injury BC; Simon Fraser University","funders":"","keywords":"Germline; DNA sequencing; Epigenetics; Lymphoma; Somatic cell; DNA methylation; Germline mutation; Mutation; KRAS","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002053275,0.0003684849,0.0002591392,0.0007957477,0.0002030644,0.0008326279,0.0003170711,0.0004430366,0.001189551],"category_scores_gemma":[0.003347765,0.0001517452,0.0002335517,0.0004252809,0.0002993928,0.0003044574,0.0003828236,0.0002702858,0.000393482],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004808371,"about_ca_system_score_gemma":0.0003817882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00102927,"about_ca_topic_score_gemma":0.001930372,"domain_scores_codex":[0.9989471,0.0003794851,0.00008224153,0.0002485036,0.0002707124,0.00007196352],"domain_scores_gemma":[0.9980269,0.0009058449,0.0003657807,0.0001103007,0.0003964229,0.0001947861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002872153,0.0004121023,0.3725691,0.0004759427,0.0002475628,0.0004102194,0.0001909183,0.005087611,0.5252612,0.0005097149,0.001016045,0.09094737],"study_design_scores_gemma":[0.0002344454,0.007106286,0.3160951,0.0001463224,0.0005252401,0.004021748,0.0004244383,0.07576548,0.5849336,0.001348556,0.009320791,0.00007788763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9760795,0.0009729186,0.01985964,0.0002118112,0.00002315201,0.0002142092,0.001052899,0.0003566147,0.001229232],"genre_scores_gemma":[0.9562333,0.0002781501,0.04117421,0.0002670584,0.00001764012,0.0001504446,0.001428117,0.00004071368,0.0004103377],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002053275,"threshold_uncertainty_score":0.01085889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.015831481033634,"score_gpt":0.3013910919382883,"score_spread":0.2855596109046543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}