{"id":"W4417002382","doi":"10.1182/blood-2025-5840","title":"Belantamab mafodotin (belamaf) in combination with bortezomib, lenalidomide, and dexamethasone (VRd) for patients (pts) with transplant-ineligible (TI) newly diagnosed multiple myeloma (NDMM): A focus on treatment efficacy and management/resolution of ocular events in the Phase 1 dreamm-9 study","year":2025,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Visual acuity; Multiple myeloma; Clinical endpoint; Dexamethasone; Dosing; Proportional hazards model; Hazard ratio; Logistic regression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008029898,0.0002603763,0.0007186641,0.0002043964,0.0002225405,0.0004933731,0.0003634749,0.0002769077,0.001635686],"category_scores_gemma":[0.000564946,0.0002505099,0.0006413381,0.0002735099,0.0002716843,0.0004802011,0.0002481631,0.001134056,0.0002868322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000863482,"about_ca_system_score_gemma":0.0008997743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000691386,"about_ca_topic_score_gemma":0.00299584,"domain_scores_codex":[0.9997146,0.000125664,0.00002383041,0.00005154802,0.00003714526,0.00004722122],"domain_scores_gemma":[0.9996144,0.00006103087,0.0001262542,0.00001974857,0.00001628961,0.0001621501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5755155,0.03593659,0.08145265,0.001319343,0.001801705,0.0003668102,0.000460025,0.003408857,0.0456639,0.0003996096,0.004512955,0.249162],"study_design_scores_gemma":[0.1650444,0.680127,0.1339517,0.0001168217,0.001216857,0.0007614682,0.0001767643,0.002059855,0.006891925,0.0002880376,0.009327248,0.0000378212],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959688,0.002179893,0.0001382222,0.0002455382,0.00003429812,0.0003005251,0.0003909756,0.00001806774,0.0007236603],"genre_scores_gemma":[0.9970769,0.0008809549,0.0004668752,0.000189748,0.00003727267,0.0002436729,0.0005133514,0.000003868018,0.000587326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001635686,"threshold_uncertainty_score":0.006264985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01556442395155511,"score_gpt":0.2910767276068326,"score_spread":0.2755123036552775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}