{"id":"W4417006713","doi":"10.1182/blood-2025-306","title":"Marstacimab prophylaxis in participants with Hemophilia A or B with inhibitors: Results from the Phase 3 BASIS trial","year":2025,"lang":"en","type":"article","venue":"Blood","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Thrombosis and Atherosclerosis Research Institute","funders":"","keywords":"Clinical endpoint; Adverse effect; Incidence (geometry); Hemostasis; Bleed; Factor IX; Observational study; Phases of clinical research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002223001,0.0006622763,0.001455226,0.0001660109,0.0002787452,0.0008600078,0.0004704122,0.0008156652,0.003983571],"category_scores_gemma":[0.001800688,0.0001728136,0.001539158,0.0003077196,0.0003375816,0.0005015925,0.0003130101,0.001381808,0.0004233432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00028726,"about_ca_system_score_gemma":0.0007707899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003734574,"about_ca_topic_score_gemma":0.0008836666,"domain_scores_codex":[0.9991546,0.0005730642,0.00004582898,0.00007655231,0.00006380145,0.00008612953],"domain_scores_gemma":[0.9986705,0.0003852512,0.0004726756,0.00009410582,0.0001099627,0.000267588],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8858486,0.005615905,0.01498996,0.002473013,0.005479491,0.0001743285,0.000123487,0.0005972516,0.006223712,0.0003178465,0.00741003,0.07074638],"study_design_scores_gemma":[0.757671,0.1580972,0.06409574,0.0004237675,0.007325953,0.0005850403,0.0001214756,0.001210799,0.001997854,0.0007869651,0.007615069,0.00006926723],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9749478,0.01801688,0.0003752103,0.0007310507,0.0001786367,0.0009113257,0.002344626,0.00008588912,0.002408592],"genre_scores_gemma":[0.9900008,0.004441039,0.0006083924,0.0007236571,0.0003235931,0.001061687,0.001986416,0.00001431378,0.0008399859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003983571,"threshold_uncertainty_score":0.01332635,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04430447316445282,"score_gpt":0.3331671014335891,"score_spread":0.2888626282691363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}