{"id":"W4417008940","doi":"10.1182/blood-2025-3581","title":"Prognostic impact of Mantle Cell Lymphoma frontline induction response assessments in the ECOG-ACRIN E1411 study of bendamustine-rituximab +/- bortezomib and maintenance with rituximab +/- lenalidomide","year":2025,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Moncton Hospital","funders":"","keywords":"Lenalidomide; Mantle cell lymphoma; Rituximab; Bortezomib; Chemoimmunotherapy; Maintenance therapy; Diffuse large B-cell lymphoma; Induction chemotherapy; Phases of clinical research; Follicular lymphoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003850684,0.0004645537,0.0006978183,0.0002861322,0.0001797818,0.0008237118,0.000600999,0.0005764625,0.001274779],"category_scores_gemma":[0.002255886,0.000216537,0.0007207237,0.0002199592,0.0003880434,0.0006028147,0.0003985011,0.0008853054,0.0002972151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005482989,"about_ca_system_score_gemma":0.0003960587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002581083,"about_ca_topic_score_gemma":0.0006318231,"domain_scores_codex":[0.9982961,0.001170212,0.0001015399,0.0002068975,0.0001338505,0.00009139167],"domain_scores_gemma":[0.9977491,0.0008854825,0.0005357887,0.0001865773,0.0001762419,0.0004667119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.4523816,0.003589331,0.4416629,0.0003242868,0.001826743,0.0001212431,0.0001212543,0.001613459,0.01601317,0.000149894,0.0009943553,0.08120169],"study_design_scores_gemma":[0.02717542,0.1535677,0.7992335,0.0001411368,0.002664269,0.0005830012,0.0001499167,0.0041489,0.008032661,0.000327726,0.003926951,0.00004878385],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967293,0.002027082,0.0001481947,0.0001023949,0.00002007626,0.0001010675,0.0002542268,0.000006681726,0.0006109471],"genre_scores_gemma":[0.9986877,0.0001570405,0.0001866776,0.0001326479,0.00003514614,0.00005430857,0.0005204921,0.000002408245,0.0002236115],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003850684,"threshold_uncertainty_score":0.02036458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01216851482288448,"score_gpt":0.3038774569581023,"score_spread":0.2917089421352178,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}