{"id":"W4417009447","doi":"10.1182/blood-2025-3418","title":"Revumenib for patients with relapsed or refractory (R/R) Nucleophosmin 1–Mutated (NPM1m) Acute Myeloid Leukemia (AML): Outcomes by prior treatment in the phase 2 AUGMENT-101 study","year":2025,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Venetoclax; Myeloid leukemia; Refractory (planetary science); Azacitidine; Salvage therapy; Hematopoietic stem cell transplantation; Phases of clinical research; Complete remission; Leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001176373,0.0007667569,0.001133877,0.0002145374,0.0001908423,0.001118748,0.0005561647,0.0007057314,0.002347863],"category_scores_gemma":[0.0006627533,0.0002082503,0.001562465,0.0002740172,0.0003182143,0.0005829689,0.0003866638,0.001716328,0.000597437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009104182,"about_ca_system_score_gemma":0.0007844821,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007815771,"about_ca_topic_score_gemma":0.002800137,"domain_scores_codex":[0.9996722,0.0001358884,0.0000215032,0.00006030895,0.00004310362,0.0000670986],"domain_scores_gemma":[0.9995576,0.00007875422,0.0001315631,0.00002896913,0.00002998832,0.0001730916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4134766,0.0114503,0.07200138,0.004516439,0.01066941,0.0007665061,0.0002210119,0.005658465,0.01714783,0.0009586422,0.02107141,0.442062],"study_design_scores_gemma":[0.4152583,0.2507645,0.2473834,0.001379953,0.01296859,0.002528945,0.0003414077,0.006772514,0.007095775,0.002107381,0.05320038,0.000198786],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9479678,0.04043023,0.0003545367,0.001310134,0.000296738,0.0007024967,0.003436207,0.0001008645,0.005401073],"genre_scores_gemma":[0.9745883,0.01341124,0.0005198678,0.001263761,0.0002643572,0.0006103238,0.006406896,0.00002037456,0.002915005],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002347863,"threshold_uncertainty_score":0.007854342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0152264564771747,"score_gpt":0.3233767125722586,"score_spread":0.308150256095084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}