{"id":"W4417013032","doi":"10.1182/blood-2025-5240","title":"Real-world evidence evaluation of the safety and efficacy of intensive chemotherapy with or without gemtuzumab ozogamicin (GO) in patients with newly diagnosed Acute Myeloid Leukemia (AML) and favorable or intermediate risk cytogenetics","year":2025,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Gemtuzumab ozogamicin; Cytarabine; Myeloid leukemia; NPM1; Chemotherapy; Chemotherapy regimen; Cytogenetics; Induction chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02018549,0.000498605,0.002251131,0.001261026,0.000295048,0.002436422,0.0009577214,0.0009914567,0.003187519],"category_scores_gemma":[0.04643447,0.0002806516,0.006264004,0.00202019,0.0009483172,0.0009360098,0.0008686201,0.001199933,0.0002617392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001615082,"about_ca_system_score_gemma":0.001812516,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007319273,"about_ca_topic_score_gemma":0.001315411,"domain_scores_codex":[0.9744226,0.0163195,0.005521835,0.001302911,0.002119658,0.0003135581],"domain_scores_gemma":[0.9325836,0.03457931,0.02568477,0.002379339,0.003763309,0.001009712],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.1975903,0.001107037,0.1244379,0.1073413,0.2323889,0.0002481885,0.0003183834,0.004668999,0.003438896,0.002201476,0.002473931,0.3237847],"study_design_scores_gemma":[0.07578391,0.09524984,0.3046984,0.06062944,0.4002942,0.001405951,0.0007687156,0.005761683,0.003756942,0.005054944,0.0463849,0.0002111302],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5337,0.4387215,0.004413078,0.005108633,0.0007333515,0.002386571,0.00638135,0.00005281626,0.008502586],"genre_scores_gemma":[0.9658418,0.02794958,0.00238182,0.001055644,0.0002984094,0.0005160135,0.001682521,0.00001202823,0.0002621436],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02018549,"threshold_uncertainty_score":0.1067523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02014469262538673,"score_gpt":0.3102496787177446,"score_spread":0.2901049860923579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}