{"id":"W4417016030","doi":"10.1182/blood-2025-1644","title":"Post-transplant maintenance with sorafenib is safe and effective in pediatric patients with har FLT3/ITD AML: A report from the Children's oncology group protocol AAML1031","year":2025,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Sorafenib; Cohort; Tolerability; Chemotherapy; Hematopoietic stem cell transplantation; Chemotherapy regimen; Transplantation; Induction chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001580555,0.0003052285,0.0004245648,0.0002906304,0.0004823577,0.0007081547,0.0005967012,0.0005612805,0.001952386],"category_scores_gemma":[0.001318709,0.0001792775,0.0004907323,0.0004808334,0.000347314,0.0003078572,0.0003914112,0.0008815352,0.0004337921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001384193,"about_ca_system_score_gemma":0.002799787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001741696,"about_ca_topic_score_gemma":0.002790507,"domain_scores_codex":[0.9991985,0.0003626929,0.00009611304,0.00008063452,0.0001327928,0.0001292872],"domain_scores_gemma":[0.9989753,0.0002194266,0.0002717654,0.00007915321,0.000161833,0.0002925256],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.0702891,0.01311916,0.4235001,0.002059333,0.0008712652,0.009108309,0.00138767,0.001799041,0.0484141,0.001739513,0.05216732,0.3755451],"study_design_scores_gemma":[0.02946213,0.0686975,0.7313042,0.0006290665,0.000804603,0.01090071,0.0006459373,0.001395866,0.0199945,0.0004466215,0.1356196,0.00009930541],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9633496,0.007778094,0.002099929,0.003534128,0.0001488293,0.007129351,0.007395501,0.0001309055,0.008433548],"genre_scores_gemma":[0.9755972,0.004131667,0.003249003,0.002245162,0.0001543346,0.006082921,0.006739893,0.00002995107,0.001769913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001952386,"threshold_uncertainty_score":0.01004308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003285458704025563,"score_gpt":0.2494593393213513,"score_spread":0.2461738806173257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}