{"id":"W4417019727","doi":"10.1182/blood-2025-2304","title":"Murine regulatory NK cells restrict allogeneic CD4⁺ T cell-driven gvhd without compromising cytotoxic function","year":2025,"lang":"en","type":"article","venue":"Blood","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"","keywords":"Cytotoxic T cell; Interleukin 21; Flow cytometry; Interleukin 12; Immune system; T cell; Cell; IL-2 receptor; Cytotoxicity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001252898,0.0002786814,0.00020056,0.0002351004,0.0001213524,0.0002821769,0.0001328828,0.0001218747,0.001687974],"category_scores_gemma":[0.00007812757,0.00009713291,0.0001830886,0.00009304863,0.0001815268,0.0001167091,0.0001900832,0.0005464046,0.0005423799],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001457911,"about_ca_system_score_gemma":0.0001339781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002220904,"about_ca_topic_score_gemma":0.0005849821,"domain_scores_codex":[0.999831,0.00001377629,0.00001405895,0.00005528809,0.00003551768,0.00005033701],"domain_scores_gemma":[0.9999167,0.000009237222,0.00002173246,0.00001265851,0.00001074238,0.00002904355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001585793,0.00003171761,0.000594063,0.00003006654,0.000004601817,0.00001413687,0.00001232733,0.000143452,0.9965417,0.00007418412,0.00008078802,0.002314367],"study_design_scores_gemma":[0.00003967508,0.0006140526,0.008422492,0.00002180591,0.00003479252,0.0002029665,0.00005930396,0.002448732,0.9833351,0.0001241879,0.004690594,0.000006238805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909468,0.0007212649,0.005108034,0.00004436743,0.00002846774,0.00006989822,0.0008851639,0.0002102098,0.001985857],"genre_scores_gemma":[0.9926072,0.0003095601,0.00346119,0.00007901777,0.000009789348,0.00009381481,0.0009265991,0.00005263618,0.00246008],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001687974,"threshold_uncertainty_score":0.005646825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007795031634183232,"score_gpt":0.2140426919671859,"score_spread":0.2062476603330027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}