{"id":"W4417028294","doi":"10.1182/bloodadvances.2025017662","title":"Hematopoietic cell transplantation for Wiskott-Aldrich syndrome: a PIDTC report","year":2025,"lang":"en","type":"article","venue":"Blood Advances","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; University of Manitoba; CancerCare Manitoba; BC Children's Hospital","funders":"National Cancer Institute; Daiichi Sankyo Europe; Grifols; National Institute of Allergy and Infectious Diseases; Office of Naval Research; Les Laboratories Pierre Fabre; National Center for Advancing Translational Sciences; Health Resources and Services Administration; Medac; Pfizer; Incyte; bluebird bio; Eli Lilly and Company; CSL Behring; Atara Biotherapeutics; Horizon Therapeutics; Memorial Sloan-Kettering Cancer Center; NHLBI Division of Intramural Research; Swedish Orphan Biovitrum; Children's Hospital of Philadelphia; National Heart, Lung, and Blood Institute; Amgen; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Hematopoietic cell; Hematopoietic stem cell transplantation; Transplantation; Hematology; Haematopoiesis; Myeloid; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008045143,0.0001038485,0.0001099344,0.00004137457,0.00009204396,0.0000188977,0.00009605761,0.00006732354,0.00001334195],"category_scores_gemma":[0.00002953781,0.0001026075,0.00009796791,0.00008373988,0.00001508863,0.00000706286,0.00001691879,0.00004406837,0.00000313112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004250022,"about_ca_system_score_gemma":0.00004765034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003819151,"about_ca_topic_score_gemma":0.00001976254,"domain_scores_codex":[0.9992994,0.00001185664,0.0002006566,0.000283136,0.00005967382,0.0001452505],"domain_scores_gemma":[0.9995955,0.00001643913,0.00007559925,0.0002157589,0.00006655655,0.00003013812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007262345,0.0003456034,0.000551358,0.0003521949,0.0000915683,0.00006771629,0.00003373356,0.00006493042,0.9940748,0.001651173,0.001232694,0.001461604],"study_design_scores_gemma":[0.0006150981,0.0002071214,0.0002051763,0.00004016073,0.0001252621,0.0003895611,0.00007237769,0.00003184914,0.7934059,0.001085828,0.2036744,0.0001472654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8256401,0.009625401,0.1508971,0.0004055348,0.001131505,0.0007210768,0.00007115632,0.00004287847,0.01146528],"genre_scores_gemma":[0.9886252,0.001027321,0.002666489,0.0001442724,0.00005819576,0.0001211178,0.0002958102,0.00001324891,0.007048394],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2024417,"threshold_uncertainty_score":0.4184211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004222881145812441,"score_gpt":0.2545017142277527,"score_spread":0.2502788330819403,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}