{"id":"W4417045526","doi":"10.1016/j.celrep.2025.116632","title":"The vaginal microbiota, symptoms, and local immune correlates in transmasculine individuals using sustained testosterone therapy","year":2025,"lang":"en","type":"article","venue":"Cell Reports","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's College Hospital; Western University","funders":"National Institute of Allergy and Infectious Diseases; National Institute on Aging; Canadian Institutes of Health Research; U.S. Department of Health and Human Services; National Institutes of Health; Canada Research Chairs; Canada Foundation for Innovation; University of California; University of Pittsburgh; School of Medicine, University of Maryland; Office of Research on Women's Health; National Institute of Nursing Research; Albert Einstein College of Medicine, Yeshiva University; Massachusetts General Hospital; Rush University","keywords":"Lactobacillus; Testosterone (patch); Immune system; Dominance (genetics); Vagina; Adverse effect; Sex organ","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001709621,0.0001449985,0.0002368443,0.0004182032,0.0003690342,0.0004324664,0.0001112485,0.0002474579,0.001690034],"category_scores_gemma":[0.0005736013,0.0001164073,0.0001498401,0.0003332105,0.0002381224,0.0001798259,0.0003129889,0.0004053071,0.0001461959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002017269,"about_ca_system_score_gemma":0.0001301963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001152366,"about_ca_topic_score_gemma":0.001858906,"domain_scores_codex":[0.9998794,0.00002661859,0.000008066149,0.00002632606,0.00002603435,0.00003362245],"domain_scores_gemma":[0.999783,0.00002285009,0.00007512998,0.0000131927,0.00001491792,0.00009101424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001995955,0.0004506393,0.9183423,0.00008522242,0.00007234084,0.001192305,0.0009746764,0.00009232351,0.04073829,0.00009782005,0.0002303111,0.03572787],"study_design_scores_gemma":[0.00001268789,0.001121531,0.9939228,0.00001801161,0.00003407735,0.001636752,0.001159028,0.0001510786,0.001446399,0.00007562814,0.0004137718,0.000008347104],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992294,0.000259661,0.00006001654,0.00002866101,0.000002805474,0.000007344574,0.0000558909,0.000002523855,0.0003536214],"genre_scores_gemma":[0.9992943,0.0001205444,0.0001100214,0.00003496576,0.000004848595,0.000007507654,0.00007207357,0.000001684235,0.0003539069],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001690034,"threshold_uncertainty_score":0.005653739,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009480377762134526,"score_gpt":0.266774853129437,"score_spread":0.2572944753673025,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}