{"id":"W4417050800","doi":"10.3390/curroncol32120673","title":"Important Role of Bacterial Metabolites in Development and Adjuvant Therapy for Hepatocellular Carcinoma","year":2025,"lang":"en","type":"article","venue":"Current Oncology","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Hepatocellular carcinoma; Immunotherapy; Epigenetics; Tumor microenvironment; Immune system; Adjuvant; Probiotic; Gut flora; Function (biology)","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001285744,0.00008884701,0.0001940049,0.00006543852,0.00002399139,0.00000458372,0.00006583493,0.00006509767,0.000008108017],"category_scores_gemma":[0.00002692887,0.00007618056,0.00003902208,0.00005018072,0.00004953299,0.000001668688,0.00006397089,0.00003742156,2.41766e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003396273,"about_ca_system_score_gemma":0.0004054524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000361671,"about_ca_topic_score_gemma":0.000199748,"domain_scores_codex":[0.9993137,0.0000360681,0.0002169007,0.00020961,0.00004288206,0.0001808879],"domain_scores_gemma":[0.9997363,0.00001560508,0.00005293016,0.0001058021,0.00004904424,0.00004032549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008246746,0.0003586459,0.5057831,0.00003585926,0.00007498965,0.000002007595,0.0001244701,1.290139e-7,0.3172789,0.0002073459,0.0001493873,0.1751605],"study_design_scores_gemma":[0.002712435,0.0003616583,0.04574188,0.00001006977,0.000008764237,0.000001203343,0.00005069706,0.00002966326,0.5319982,0.0002181486,0.418803,0.00006426186],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9529935,0.04625262,0.00003425545,0.00003360999,0.0001623019,0.0004017922,0.00002698383,0.000001840118,0.0000931222],"genre_scores_gemma":[0.9970685,0.002161541,0.0002563518,0.00001262058,0.00004631306,0.0002203796,0.0002014077,0.000005410149,0.00002746576],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4600412,"threshold_uncertainty_score":0.3106553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0391581324510632,"score_gpt":0.3619750997696435,"score_spread":0.3228169673185803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}