{"id":"W4417069991","doi":"10.1093/ageing/afaf318.003","title":"Clinical Trials For New Therapeutics In Alzheimer’s Disease – Ensuring Ireland Is Research-Ready","year":2025,"lang":"en","type":"article","venue":"Age and Ageing","topic":"Clinical practice guidelines implementation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"","keywords":"Clinical trial; Workforce; Psychological intervention; Dementia; Disease; Irish; Capacity building; Intervention (counseling); Investment (military)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.472409,0.001028972,0.002892554,0.003056217,0.004723392,0.03088153,0.007425332,0.0102701,0.02562414],"category_scores_gemma":[0.4615341,0.002090077,0.002972115,0.003481721,0.01313737,0.02289113,0.03014093,0.02036171,0.01612581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01847669,"about_ca_system_score_gemma":0.2438095,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009510489,"about_ca_topic_score_gemma":0.01164416,"domain_scores_codex":[0.5567048,0.3282551,0.03398763,0.01461177,0.03720891,0.0292318],"domain_scores_gemma":[0.3261543,0.1685093,0.04467585,0.09537054,0.1788821,0.186408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003322245,0.001072227,0.01449855,0.008506168,0.0005372867,0.0008910217,0.008154464,0.001252798,0.00360245,0.07154774,0.5226718,0.3639433],"study_design_scores_gemma":[0.002722262,0.002233136,0.01735966,0.009438683,0.0002519992,0.0007014498,0.006788862,0.0007711243,0.002099021,0.04047811,0.9167824,0.0003732064],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01479488,0.01002034,0.02403026,0.8247995,0.01769193,0.007866662,0.002456478,0.001567026,0.09677304],"genre_scores_gemma":[0.2673123,0.01211479,0.136568,0.5186179,0.01047155,0.0215013,0.004201812,0.002073951,0.02713845],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.472409,"threshold_uncertainty_score":0.6506137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.8059871128996119,"score_gpt":0.6625545118152457,"score_spread":0.1434326010843662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}