{"id":"W4417076566","doi":"10.1126/science.adr6322","title":"Macrophage MR1 antigen presentation promotes MAIT cell immunity and lung microbiota modulation","year":2025,"lang":"en","type":"article","venue":"Science","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Australian Research Council; National Health and Medical Research Council; Horizon 2020 Framework Programme; National Institutes of Health; Cass Foundation","keywords":"Antigen presentation; Macrophage; Antigen; Cell; Major histocompatibility complex; Immune system; Inflammation; Innate immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003038658,0.0003019575,0.0003375357,0.000276307,0.0001726726,0.0004069663,0.0001347151,0.0003025326,0.001517097],"category_scores_gemma":[0.0002374978,0.0001371259,0.0002421991,0.0000965178,0.0003327575,0.0003123173,0.0003501572,0.0007338063,0.0005351989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001775747,"about_ca_system_score_gemma":0.0001531827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001561557,"about_ca_topic_score_gemma":0.0001698938,"domain_scores_codex":[0.9996852,0.00008523647,0.00002049082,0.00006013617,0.00003878686,0.0001102063],"domain_scores_gemma":[0.9997924,0.00002381939,0.00005813661,0.00001774895,0.00003281725,0.00007507976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000245743,0.00001888857,0.0007014628,0.00003744952,0.000002149279,0.00008617568,0.00002845501,0.00001685349,0.9974225,0.00009318817,0.00002574592,0.001321521],"study_design_scores_gemma":[0.00006087681,0.001092225,0.04110816,0.00003681936,0.00003412575,0.001281736,0.0002669603,0.001471048,0.9498733,0.0003322454,0.004430274,0.00001211899],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937224,0.002993925,0.001843941,0.0001570445,0.00003824314,0.00002025192,0.00007208779,0.00004416804,0.001107932],"genre_scores_gemma":[0.9971862,0.0005546631,0.0008537901,0.00005242913,0.00003167272,0.00001575056,0.00006386716,0.000008712351,0.00123285],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001517097,"threshold_uncertainty_score":0.005075157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006152067222967131,"score_gpt":0.2527670434524139,"score_spread":0.2466149762294468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}