{"id":"W4417086303","doi":"10.1186/s12974-025-03630-0","title":"Early peripheral blood gene expression predicts 90-day outcomes following subarachnoid hemorrhage","year":2025,"lang":"en","type":"article","venue":"Journal of Neuroinflammation","topic":"Intracranial Aneurysms: Treatment and Complications","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta Hospital; University of Alberta","funders":"National Institute of Neurological Disorders and Stroke; University of California, Davis; National Institutes of Health","keywords":"Subarachnoid hemorrhage; Neurology; Peripheral blood; Peripheral; Gene expression; Subarachnoid haemorrhage; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001892643,0.0001597325,0.0003184254,0.0002315374,0.0001566539,0.00005627736,0.0001253298,0.00007528196,0.00003140508],"category_scores_gemma":[0.0001736213,0.0001218739,0.0002949079,0.0002079214,0.00001935608,0.0003274232,0.00002697079,0.0002512928,0.00001049458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000531513,"about_ca_system_score_gemma":0.0000967919,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003260313,"about_ca_topic_score_gemma":8.869312e-7,"domain_scores_codex":[0.9986613,0.00006932425,0.0005900795,0.0001480783,0.0003610984,0.0001701645],"domain_scores_gemma":[0.9991081,0.00007587839,0.0003109617,0.0002316212,0.0001807138,0.00009266924],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001381832,0.000297637,0.07260673,0.00006606335,0.00008995842,0.0007009615,0.00027422,0.00005144496,0.9215283,0.0001624883,0.00009924228,0.003984792],"study_design_scores_gemma":[0.004214197,0.0006568913,0.7648197,0.0001379398,0.0009902423,0.0005126356,0.00004606996,0.0008248952,0.2269946,0.0005207182,0.0001387686,0.0001432643],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931977,0.0001326975,0.001823493,0.002800511,0.0004871154,0.0002774687,0.000002012109,0.00004889824,0.001230101],"genre_scores_gemma":[0.995241,0.000008862903,0.002775405,0.0001102138,0.0002033492,0.000008326383,0.000009774824,0.00001579359,0.001627225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6945336,"threshold_uncertainty_score":0.4969875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01057719571856982,"score_gpt":0.2536256960331701,"score_spread":0.2430485003146003,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}