{"id":"W4417086303","doi":"10.1186/s12974-025-03630-0","title":"Early peripheral blood gene expression predicts 90-day outcomes following subarachnoid hemorrhage","year":2025,"lang":"en","type":"article","venue":"Journal of Neuroinflammation","topic":"Intracranial Aneurysms: Treatment and Complications","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta Hospital; University of Alberta","funders":"National Institute of Neurological Disorders and Stroke; University of California, Davis; National Institutes of Health","keywords":"Subarachnoid hemorrhage; Neurology; Peripheral blood; Peripheral; Gene expression; Subarachnoid haemorrhage; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003683236,0.0002210158,0.0002645378,0.000390816,0.000104972,0.0003662823,0.0001290652,0.0001920782,0.0007773619],"category_scores_gemma":[0.00118958,0.00007452261,0.000184563,0.0003448021,0.0001850621,0.0001113355,0.000164952,0.0002890801,0.0002046862],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001846173,"about_ca_system_score_gemma":0.0002573112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009641346,"about_ca_topic_score_gemma":0.001038974,"domain_scores_codex":[0.9998925,0.00002874328,0.000007230993,0.00002923939,0.00002049816,0.00002176741],"domain_scores_gemma":[0.9994345,0.0002326034,0.0001663069,0.00003263694,0.00007160156,0.00006226139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001591747,0.00007577248,0.9745447,0.00004229602,0.0001070764,0.000108962,0.0000408905,0.001440883,0.01081143,0.00003026869,0.0001748036,0.01103109],"study_design_scores_gemma":[0.00001759451,0.0002464592,0.9913651,0.000009682831,0.00007917875,0.000198566,0.0000384477,0.004397891,0.003346243,0.0001167576,0.0001790498,0.000005020264],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985908,0.0002802749,0.0006135914,0.00002886891,0.000003911109,0.000006687543,0.0002989189,0.00001373699,0.0001631941],"genre_scores_gemma":[0.998652,0.0001544128,0.0005489038,0.00001565177,0.000005460387,0.00001127963,0.0004615909,0.000003222366,0.0001474636],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009641346,"threshold_uncertainty_score":0.002600551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01057719571856982,"score_gpt":0.2536256960331701,"score_spread":0.2430485003146003,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}