{"id":"W4417123733","doi":"10.3390/stresses5040069","title":"Exploring How Reactive Oxygen Species Contribute to Cancer via Oxidative Stress","year":2025,"lang":"en","type":"article","venue":"Stresses","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Universidad de Zaragoza","keywords":"Oxidative stress; Reactive oxygen species; Cancer; Epigenetics; Oxidative phosphorylation; Tumor microenvironment; Function (biology); Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005189913,0.0001952929,0.000228987,0.0000783803,0.0001150305,0.00005596189,0.0002128079,0.00007435546,0.00002901784],"category_scores_gemma":[0.000143764,0.0001862984,0.00008161829,0.0001977879,0.00006334244,0.00001557876,0.000168562,0.00008845795,0.000003935756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003610716,"about_ca_system_score_gemma":0.000134493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002754465,"about_ca_topic_score_gemma":0.001157313,"domain_scores_codex":[0.9989765,0.00003936445,0.000125167,0.0004136039,0.0001279461,0.0003174382],"domain_scores_gemma":[0.9992771,0.00002462703,0.00006332458,0.0003211446,0.0002166492,0.00009713829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001884784,0.0000527649,0.001242029,0.00004507362,0.0002775497,0.00000192751,0.0002609373,0.00009350292,0.959272,0.0002845206,0.01960015,0.01868109],"study_design_scores_gemma":[0.0002773649,0.00003669115,0.008547902,0.00005765402,0.00003347181,3.894335e-7,0.0005395206,0.000001028163,0.604142,0.00003269812,0.3861924,0.0001388933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.977343,0.009746568,0.002822404,0.002268971,0.002856198,0.000444903,0.0009288568,0.00003733944,0.003551746],"genre_scores_gemma":[0.9832603,0.006402262,0.0001655309,0.0003766825,0.001824167,0.0003163194,0.0001549826,0.00002032859,0.007479452],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3665922,"threshold_uncertainty_score":0.759703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03303161190545458,"score_gpt":0.2782285551358625,"score_spread":0.2451969432304079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}