{"id":"W4417129987","doi":"10.58931/cht.2025.4379","title":"Unique Toxicities of Novel Myeloma Therapies: Focus on Belantamab Mafodotin, Talquetamab, and Selinexor","year":2025,"lang":"","type":"article","venue":"Canadian Hematology Today","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Surrey Place Centre","funders":"","keywords":"Multiple myeloma; Toxicity; Chimeric antigen receptor; Drug; Disease; Monoclonal antibody; Adverse effect; Bortezomib","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001130107,0.0002847402,0.0006140902,0.000405604,0.0002939221,0.0007374335,0.000257004,0.0002877105,0.001297232],"category_scores_gemma":[0.0005726784,0.000102035,0.0004227589,0.0003510035,0.0003823447,0.0006808923,0.0004876897,0.001183417,0.000231365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001141281,"about_ca_system_score_gemma":0.0006372177,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000680807,"about_ca_topic_score_gemma":0.004094944,"domain_scores_codex":[0.9997444,0.00008449085,0.00002106968,0.00002978555,0.00007875818,0.00004144431],"domain_scores_gemma":[0.9996653,0.0001139019,0.00006652274,0.00001483782,0.00007737162,0.0000621922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008592179,0.000183929,0.003777164,0.001307071,0.000177504,0.001721471,0.000186338,0.001327854,0.02413079,0.008040348,0.01858008,0.9397082],"study_design_scores_gemma":[0.0007374305,0.004936819,0.0340021,0.001183123,0.0005189372,0.02764147,0.0003097478,0.003243293,0.02735601,0.01117344,0.8888187,0.00007898232],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1157182,0.8238588,0.005140594,0.02664038,0.001053055,0.00006556364,0.000150108,0.0001736391,0.02719957],"genre_scores_gemma":[0.5034838,0.46349,0.006931218,0.01057784,0.004446038,0.00007740529,0.0003443224,0.00008263248,0.01056661],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001297232,"threshold_uncertainty_score":0.008280575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02014622794762031,"score_gpt":0.2911424927427976,"score_spread":0.2709962647951772,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}