{"id":"W4417136133","doi":"10.1139/cjc-2025-0158","title":"Electrochemical and surface analysis of interactions between Cu(II) and Zn(II) metal ions with TDP-43 protein immobilized on gold surfaces","year":2025,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Tech University; Trent University","funders":"Natural Sciences and Engineering Research Council of Canada; Trent University","keywords":"Electrochemistry; Redox; Ion; Copper; Oxidative stress; Metal; Oxygen; Metal ions in aqueous solution; Reactive oxygen species","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002517917,0.0003596593,0.0003403846,0.0002280909,0.0002451389,0.0002547003,0.0005344396,0.0006469828,0.0008534591],"category_scores_gemma":[0.0004144688,0.0002388856,0.0002153679,0.0003094982,0.0002724695,0.0001849284,0.0002742684,0.0005322369,0.0002164018],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002641802,"about_ca_system_score_gemma":0.0001316722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00134827,"about_ca_topic_score_gemma":0.00111795,"domain_scores_codex":[0.9996871,0.00005831856,0.00001291236,0.00006252099,0.0001247812,0.00005450963],"domain_scores_gemma":[0.999798,0.00007024092,0.00002439045,0.00001421622,0.00006457747,0.00002855212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000514377,0.00001885819,0.0001891314,0.00003808771,0.00001099725,0.0000461756,0.00005294408,0.00005133136,0.9983287,0.00004337991,0.00002914446,0.001139876],"study_design_scores_gemma":[0.00001303829,0.0002285004,0.004610715,0.000006439169,0.00002357755,0.0002104057,0.0001376072,0.002964891,0.9908702,0.00006418982,0.0008605766,0.000009901648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991012,0.001447527,0.005662802,0.000121511,0.00004900912,0.00002210163,0.0001246481,0.00006264131,0.001497768],"genre_scores_gemma":[0.9896734,0.0006922177,0.007476921,0.00007796139,0.00001741981,0.00003408614,0.0001490151,0.00001039185,0.001868617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00134827,"threshold_uncertainty_score":0.002855062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0133806045900678,"score_gpt":0.2755622843421458,"score_spread":0.262181679752078,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}