{"id":"W4417198362","doi":"10.1016/j.celbio.2025.100280","title":"Engineered cells for cardiovascular diseases","year":2025,"lang":"en","type":"article","venue":"Cell Biomaterials","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University Health Network","funders":"Basic and Applied Basic Research Foundation of Guangdong Province; Science, Technology and Innovation Commission of Shenzhen Municipality; National Natural Science Foundation of China","keywords":"Induced pluripotent stem cell; Mesenchymal stem cell; Regenerative medicine; Stem cell; Cell therapy; Function (biology); Genetic enhancement; Stem cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003167846,0.0003391626,0.0001653201,0.000405795,0.0001738557,0.0006577144,0.0003361632,0.0004622774,0.002933689],"category_scores_gemma":[0.0002078236,0.0001284828,0.000254909,0.0001582137,0.0002500832,0.0003388652,0.0004174093,0.0007066143,0.0009569734],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001984455,"about_ca_system_score_gemma":0.0002428229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001924428,"about_ca_topic_score_gemma":0.0005292489,"domain_scores_codex":[0.9998829,0.00001740176,0.00001072541,0.00001843263,0.00005400108,0.00001647578],"domain_scores_gemma":[0.9999163,0.00002049968,0.00001704096,0.00001135089,0.00001661924,0.00001819217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001197554,0.0002080992,0.000601483,0.0004223112,0.00003543689,0.0003988197,0.0001128665,0.0005235866,0.9169419,0.01556536,0.002279709,0.06279068],"study_design_scores_gemma":[0.00007844318,0.0004894309,0.001520464,0.0001688174,0.000114482,0.001508638,0.00007971792,0.001634926,0.7855518,0.004095052,0.2047396,0.00001845841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6478444,0.1205814,0.1373611,0.003285068,0.004646866,0.0007285395,0.001745903,0.0008096273,0.08299701],"genre_scores_gemma":[0.8473443,0.04162711,0.06071161,0.001603618,0.0003870657,0.0003819627,0.00146101,0.0001430813,0.04634011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002933689,"threshold_uncertainty_score":0.009814143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008162134529687125,"score_gpt":0.2404966615148294,"score_spread":0.2323345269851423,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}