{"id":"W4417200845","doi":"10.1091/mbc.e25-09-0443","title":"Membrane curvature elastic stress triggers recruitment of PML-II onto the inner nuclear membrane","year":2025,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Inner membrane; Diacylglycerol kinase; Nuclear membrane; Membrane curvature; Lamin; Membrane; Cell membrane; Promyelocytic leukemia protein; Cell nucleus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001684217,0.0001835786,0.0002347655,0.00004589343,0.0001327119,0.000005403385,0.000529773,0.0003039371,0.00003667131],"category_scores_gemma":[0.00006980597,0.0001081484,0.000232067,0.0001819823,0.0003209615,0.000001958985,0.000317305,0.0001900076,0.000002239971],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001311813,"about_ca_system_score_gemma":0.00005463508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003955865,"about_ca_topic_score_gemma":0.00002104649,"domain_scores_codex":[0.9989195,0.0002098242,0.0002714837,0.0002992664,0.00009612608,0.0002038387],"domain_scores_gemma":[0.9989658,0.00002251991,0.0001877803,0.000709377,0.00008638743,0.00002812804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001942295,0.00006902985,0.0001866817,0.00006038893,0.0001809797,6.083521e-7,0.00006509908,0.0001889326,0.9956738,0.001651045,0.001084689,0.0006445165],"study_design_scores_gemma":[0.0005470224,0.0002624458,0.0003398144,0.0000286965,0.0001284697,0.000002893274,0.00006723215,0.00002562072,0.9235765,0.0002510867,0.07466704,0.0001031515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906228,0.001550347,0.0003301879,0.001136027,0.0007045984,0.0004680482,0.00003974488,0.000008863026,0.005139338],"genre_scores_gemma":[0.9973492,0.0001433702,0.0002186369,0.000809115,0.00004813798,0.00001142643,0.00004690346,0.00001927152,0.001353929],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07358235,"threshold_uncertainty_score":0.4410162,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006262306795593005,"score_gpt":0.2337506156014169,"score_spread":0.2274883088058239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}