{"id":"W4417201219","doi":"10.1158/1557-3265.earlyonsetca25-pr002","title":"Abstract PR002: Clinical, pathological, and molecular differences in early- and late-onset colorectal cancer: Results from a multicenter study","year":2025,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Colorectal Cancer Screening and Detection","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Colorectal cancer; Incidence (geometry); Colorectal adenoma; Odds ratio; Adenoma; Stage (stratigraphy); Cohort; Cohort study","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003068222,0.0004735358,0.0003956983,0.0006205415,0.0004059906,0.00069603,0.0005766967,0.0005805787,0.001443242],"category_scores_gemma":[0.003630486,0.000265713,0.000688655,0.0009863094,0.0003231508,0.0006050452,0.0006285794,0.0004163621,0.0004058261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002270862,"about_ca_system_score_gemma":0.000319242,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00209855,"about_ca_topic_score_gemma":0.002037756,"domain_scores_codex":[0.9987041,0.0005658212,0.0001273227,0.000342859,0.0001628527,0.0000970867],"domain_scores_gemma":[0.9962503,0.0005493622,0.001551506,0.0004946829,0.0005491656,0.0006049963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002909534,0.0002282757,0.9940146,0.00002792328,0.0002497317,0.00007050957,0.00009371212,0.00002235665,0.0007093309,0.00001036369,0.0002065393,0.001457121],"study_design_scores_gemma":[0.0002633706,0.0009681589,0.9977174,0.000008044311,0.0001512276,0.000191572,0.0001765519,0.00009096256,0.000126608,0.00001132002,0.0002893059,0.000005712535],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981974,0.0002826533,0.0001335695,0.00004170055,0.000008887599,0.00004782077,0.001022674,0.00000454466,0.0002606809],"genre_scores_gemma":[0.9982066,0.00008842674,0.0001811966,0.00005331521,0.00002768632,0.00004932864,0.001189922,0.000005070398,0.0001985152],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003068222,"threshold_uncertainty_score":0.01622653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1865580994381978,"score_gpt":0.5056002351971923,"score_spread":0.3190421357589945,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}