{"id":"W4417239819","doi":"10.1128/mbio.02141-25","title":"Immunomodulatory functions of fungal melanins in respiratory infections","year":2025,"lang":"en","type":"review","venue":"mBio","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Columbia College","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Antifungal; Immune system; Respiratory tract; Melanin; Virulence; Pathogenicity; Respiratory tract infections","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003673186,0.0002582229,0.001511017,0.0005083698,0.00006094265,0.000006514139,0.0001091455,0.0003927084,0.0002231662],"category_scores_gemma":[0.0003316994,0.0002209496,0.0006131904,0.0007994598,0.0001236695,0.00004365058,0.00006214168,0.000663965,0.00008862214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003062061,"about_ca_system_score_gemma":0.001545976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006388739,"about_ca_topic_score_gemma":0.0003462623,"domain_scores_codex":[0.9983022,0.0001510417,0.0007754143,0.0003707442,0.0001824355,0.0002181223],"domain_scores_gemma":[0.998718,0.0002014208,0.0001851375,0.0007238204,0.0001054457,0.0000662189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005854602,0.001204874,0.03982228,0.07687682,0.0005359917,0.00007634452,0.00007617239,7.453791e-7,0.00003533377,0.000750649,0.006698002,0.8738642],"study_design_scores_gemma":[0.0002985285,0.0001721148,0.01773567,0.0155251,0.0006720067,0.000005429274,0.00003235623,3.12677e-7,0.000003562184,0.00001417433,0.9653805,0.0001601884],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007330534,0.9835657,0.00003375669,0.000008485008,0.0003746088,0.0006835255,0.0000970085,0.00004298617,0.01446085],"genre_scores_gemma":[0.002566339,0.9906504,0.00001308091,0.00004728851,0.00009555141,0.00007964807,0.00007612256,0.00002402645,0.006447514],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9586825,"threshold_uncertainty_score":0.9010064,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04454848308792451,"score_gpt":0.3624773418982764,"score_spread":0.3179288588103519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}