{"id":"W4417244599","doi":"10.54434/candj.209","title":"Considerations of Gut Microbiome and Cancer—Part 1: Exploring Its Role in Tumorigenesis and Treatment Responses","year":2025,"lang":"","type":"article","venue":"CAND Journal","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Microbiome; Gut microbiome; Gut flora; Immune system; Carcinogenesis; Cancer; Human microbiome; Mechanism (biology); Immunotherapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002266578,0.0001988296,0.0003442022,0.0002260935,0.0002812707,0.00007138733,0.00004767916,0.0001270421,0.00004375046],"category_scores_gemma":[0.00005580837,0.0001872943,0.00005928504,0.0001151274,0.0001713028,0.00001190117,0.00005856568,0.000124244,3.307813e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001176911,"about_ca_system_score_gemma":0.001361902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002239107,"about_ca_topic_score_gemma":0.001192941,"domain_scores_codex":[0.998722,0.0001507737,0.0004988018,0.0002849049,0.00004357519,0.0003000034],"domain_scores_gemma":[0.9993851,0.00004582389,0.0001610456,0.0001302727,0.0001274208,0.0001502999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003026414,0.00009532814,0.02272733,0.0001015353,0.000141902,0.00002281632,0.000618637,0.00001478184,0.9658972,0.00008632985,0.0004319999,0.009559521],"study_design_scores_gemma":[0.005183329,0.0009825996,0.07094505,0.001031422,0.0002562876,0.0006716636,0.00237215,0.00002776403,0.8283132,0.0001432014,0.08964947,0.0004238138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.887742,0.1100452,0.000006080192,0.001418298,0.0003708437,0.000174451,0.0001365199,0.000001250943,0.0001053133],"genre_scores_gemma":[0.8667069,0.1320611,0.00008157158,0.0001365466,0.0001460943,0.00001692829,0.000005148213,0.000009335515,0.0008363678],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1375839,"threshold_uncertainty_score":0.7637641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04372319119645485,"score_gpt":0.3081787597192479,"score_spread":0.2644555685227931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}