{"id":"W4417280346","doi":"10.1182/bloodadvances.2025017393","title":"Impact of age on graft-versus-host disease and overall survival in pediatric hematopoietic cell transplant recipients","year":2025,"lang":"en","type":"article","venue":"Blood Advances","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cancer Moonshot; National Institute of Allergy and Infectious Diseases; Office of Naval Research; Legend Biotech; Pharmacyclics; Takeda Oncology; National Institutes of Health; MorphoSys; Seagen; Health Resources and Services Administration; Syndax Pharmaceuticals; Astellas Pharma; Adaptive Biotechnologies; Pfizer; Incyte; Kiadis Pharma; bluebird bio; Medac; Jazz Pharmaceuticals; BeiGene; HistoGenetics; Atara Biotherapeutics; CareDx; Actinium Pharmaceuticals; National Cancer Institute; Gilead Sciences; Moonshot Research and Development Program; Sanofi; CSL Behring; Bristol-Myers Squibb; AstraZeneca; Swedish Orphan Biovitrum; Omeros Corporation; Vertex Pharmaceuticals; Alexion Pharmaceuticals; Mallinckrodt Pharmaceuticals; U.S. Department of Health and Human Services; Astellas Pharma US; Gateway for Cancer Research; Amgen; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation","keywords":"Incidence (geometry); Disease; Hematopoietic stem cell transplantation; Transplantation; Overall survival; Young adult; Hematopoietic cell; Graft-versus-host disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006651959,0.0001976973,0.0002207183,0.0005121344,0.0001616871,0.0003760185,0.0001515655,0.0002088329,0.001724805],"category_scores_gemma":[0.001475,0.00009007848,0.0003982419,0.0004951726,0.0001470165,0.0004078508,0.0002887559,0.000378298,0.0001520016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002393432,"about_ca_system_score_gemma":0.0003067059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001104283,"about_ca_topic_score_gemma":0.001142084,"domain_scores_codex":[0.9996761,0.000097073,0.00003327085,0.00005077148,0.00007064953,0.00007210758],"domain_scores_gemma":[0.9987614,0.0003215075,0.0005323327,0.00004779598,0.000083998,0.0002529659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000106353,0.000008782794,0.9987205,0.000004225548,0.00002407065,0.0000402138,0.000007754633,0.00005149048,0.00007474457,0.000007548301,0.00003575482,0.000918605],"study_design_scores_gemma":[0.00000455096,0.0001326726,0.998993,0.000005216363,0.00003458533,0.0003269913,0.00004017677,0.000198302,0.00008792688,0.00001228919,0.0001630096,0.000001269538],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989012,0.0004877956,0.00007391329,0.00002654691,0.000005500661,0.000002267857,0.0002404872,0.000002159395,0.000260051],"genre_scores_gemma":[0.9995011,0.0001406447,0.00004711112,0.000009188198,0.000009289717,0.000002664144,0.000231543,0.000001291418,0.00005705215],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001724805,"threshold_uncertainty_score":0.005770087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0128392917706969,"score_gpt":0.2893509076232866,"score_spread":0.2765116158525897,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}