{"id":"W4417289966","doi":"10.1016/j.tplants.2025.11.003","title":"The plant pyruvate hub","year":2025,"lang":"en","type":"review","venue":"Trends in Plant Science","topic":"Plant Gene Expression Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; The Scarborough Hospital","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Pyruvate dehydrogenase complex; Terpenoid; Phosphoenolpyruvate carboxykinase; Biosynthesis; Acetyl-CoA; Metabolic pathway; Allosteric regulation; Fatty acid synthesis; Citric acid cycle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009428585,0.001461556,0.001568246,0.001424474,0.0004704263,0.002380769,0.001397269,0.001683499,0.007447357],"category_scores_gemma":[0.0007258014,0.0005853337,0.0004765204,0.001943641,0.001113744,0.00311868,0.002104661,0.004831308,0.007288205],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001382302,"about_ca_system_score_gemma":0.001488918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000744907,"about_ca_topic_score_gemma":0.001107412,"domain_scores_codex":[0.9997563,0.00004117553,0.00002180999,0.00007145984,0.00006322381,0.00004606135],"domain_scores_gemma":[0.9997965,0.00005211726,0.00003326337,0.00001383816,0.00004606215,0.00005831559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002945168,0.00008114597,0.0001246417,0.008077155,0.00009288758,0.0003134073,0.00003683677,0.0006502613,0.00355209,0.04426923,0.1273887,0.8151191],"study_design_scores_gemma":[0.00001647322,0.00003489231,0.00009806827,0.0003671717,0.00002389541,0.0002209921,0.000009699846,0.00005512207,0.0005233088,0.003548015,0.9950935,0.000008843941],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001370233,0.9911579,0.0008184998,0.001215778,0.002045135,0.000009328543,0.00006084326,0.00004013532,0.004515334],"genre_scores_gemma":[0.002261373,0.9877588,0.0007965838,0.001679655,0.001162147,0.00002302743,0.0001761466,0.00001541375,0.006126799],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007447357,"threshold_uncertainty_score":0.02491391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03507099991703145,"score_gpt":0.3443498935885186,"score_spread":0.3092788936714872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}