{"id":"W4417298624","doi":"10.1038/s42003-025-09145-x","title":"Structural dependence of ProQ-mRNA interactions in live bacterial cells","year":2025,"lang":"en","type":"article","venue":"Communications Biology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Sherbrooke","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Messenger RNA; Bacteria; Regulator; Exponential growth; Residue (chemistry); Transfer RNA; RNA; Regulation of gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002085289,0.0003051891,0.0003433594,0.0001498503,0.0002362655,0.0004387688,0.0002811787,0.0003619565,0.001070098],"category_scores_gemma":[0.0003815908,0.0002017568,0.000195377,0.0001702041,0.0002844358,0.0003707782,0.0003245936,0.0006428754,0.0004535849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003793095,"about_ca_system_score_gemma":0.0001471662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009109782,"about_ca_topic_score_gemma":0.0009631315,"domain_scores_codex":[0.999651,0.00005145594,0.000018888,0.0001086314,0.0001171527,0.00005301405],"domain_scores_gemma":[0.999504,0.0002382972,0.00008758076,0.00004289225,0.00006992756,0.00005732457],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002661216,0.000006947993,0.0001156673,0.000016478,0.000002814456,0.00001419096,0.00001948005,0.00004398988,0.9994665,0.00002602027,0.000007111702,0.0002542611],"study_design_scores_gemma":[0.000003251974,0.00008187771,0.003407778,0.000003371169,0.000005882149,0.00005032908,0.00004512231,0.001465351,0.9945489,0.00002670259,0.000356577,0.000004978974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877459,0.0008230245,0.009568728,0.00007478755,0.00001986187,0.00002282641,0.0003605166,0.00007126002,0.001312986],"genre_scores_gemma":[0.9907215,0.000648545,0.005728326,0.00006818777,0.00001308717,0.00007844908,0.0007679712,0.00007787467,0.001896171],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001070098,"threshold_uncertainty_score":0.003579855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01926683003013725,"score_gpt":0.3053783071792092,"score_spread":0.2861114771490719,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}